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7Q45

Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of Myelin transcription factor 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, C, E)
E3 ubiquitin-protein ligase HERC2polymer40542770.63UniProt (O95714)
Pfam (PF25390)
Homo sapiens (Human)HECT domain and RCC1-like domain-containing protein 2,HECT-type E3 ubiquitin transferase HERC2
2D, E, F
(B, D, F)
Myelin transcription factor 1polymer141708.73UniProt (Q01538)Homo sapiensMyT1,Myelin transcription factor I,MyTI,PLPB1,Proteolipid protein-binding protein
3G, H, I
(C, E)
CITRIC ACIDnon-polymer192.13Chemie (CIT)
4J, K, L, M, N...
(A, C, E, B, D...)
waterwater18.0840Chemie (HOH)
Sequence modifications
A, C, E: 2938 - 3342 (UniProt: O95714)
PDBExternal DatabaseDetails
Ala 2939Asn 2939conflict
Met 2940Ser 2940conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight133437.9
Non-Polymers*Number of molecules3
Total formula weight576.4
All*Total formula weight134014.2
*Water molecules are not included.

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PDB entries from 2026-02-11

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