7Q44
Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of deubiquitinase USP35
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, E) | E3 ubiquitin-protein ligase HERC2 | polymer | 405 | 42770.6 | 3 | UniProt (O95714) Pfam (PF25390) | Homo sapiens (Human) | HECT domain and RCC1-like domain-containing protein 2,HECT-type E3 ubiquitin transferase HERC2 |
| 2 | D, E, F (D, B, F) | Deubiquitinase USP35 peptide | polymer | 15 | 1554.5 | 3 | UniProt (Q9P2H5) | Homo sapiens | Deubiquitinating enzyme 35,Ubiquitin thioesterase 35,Ubiquitin-specific-processing protease 35, Ubiquitin carboxyl-terminal hydrolase 35 |
| 3 | G, H, I (C, E) | CITRIC ACID | non-polymer | 192.1 | 3 | Chemie (CIT) | |||
| 4 | J, K, L, M, N... (A, C, E, D, B...) | water | water | 18.0 | 644 | Chemie (HOH) |
Sequence modifications
A, C, E: 2941 - 3342 (UniProt: O95714)
| PDB | External Database | Details |
|---|---|---|
| Gly 2938 | - | expression tag |
| Ala 2939 | - | expression tag |
| Met 2940 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 132975.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 576.4 | |
| All* | Total formula weight | 133551.5 |
