7Q3L
Human 17S U2 snRNP 5' domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Splicing factor 3B subunit 2 | polymer | 895 | 100377.8 | 1 | UniProt (Q13435) Pfam (PF02037) Pfam (PF04037) Pfam (PF04046) | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 145 kDa subunit,SF3b145,Spliceosome-associated protein 145,SAP 145 |
| 2 | B (C) | Splicing factor 3B subunit 3 | polymer | 1217 | 135718.8 | 1 | UniProt (Q15393) Pfam (PF10433) Pfam (PF23726) Pfam (PF03178) | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 130 kDa subunit,SF3b130,STAF130,Spliceosome-associated protein 130,SAP 130 |
| 3 | C (E) | Splicing factor 3B subunit 5 | polymer | 86 | 10149.4 | 1 | UniProt (Q9BWJ5) Pfam (PF07189) | Homo sapiens (human) | SF3b5,Pre-mRNA-splicing factor SF3b 10 kDa subunit |
| 4 | D (G) | PHD finger-like domain-containing protein 5A | polymer | 110 | 12427.5 | 1 | UniProt (Q7RTV0) Pfam (PF03660) | Homo sapiens (human) | PHD finger-like domain protein 5A,Splicing factor 3B-associated 14 kDa protein,SF3b14b |
| 5 | E (2) | U2 snRNA | polymer | 188 | 60186.4 | 1 | GenBank (NR_002716) | Homo sapiens (human) | |
| 6 | F (9) | Splicing factor 3A subunit 3 | polymer | 501 | 58934.8 | 1 | UniProt (Q12874) Pfam (PF12108) Pfam (PF16837) Pfam (PF13297) Pfam (PF11931) | Homo sapiens (human) | SF3a60,Spliceosome-associated protein 61,SAP 61 |
| 7 | G (q) | HIV Tat-specific factor 1 | polymer | 803 | 90888.3 | 1 | UniProt (O43719) Pfam (PF00076) | Homo sapiens (human) | Tat-SF1 |
| 8 | H (A) | Splicing factor 3B subunit 1 | polymer | 1304 | 146024.9 | 1 | UniProt (O75533) Pfam (PF08920) Pfam (PF22646) | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 155 kDa subunit,SF3b155,Spliceosome-associated protein 155,SAP 155 |
| 9 | I (p) | Probable ATP-dependent RNA helicase DDX46 | polymer | 1031 | 117576.5 | 1 | UniProt (Q7L014) Pfam (PF00270) Pfam (PF00271) Pfam (PF23469) | Homo sapiens (human) | DEAD box protein 46,PRP5 homolog |
| 10 | J, K, L, M (G, 9) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 11 | N, O, P, Q, R (B, C, E, G, A) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
q: 2 - 755 (UniProt: O43719)
| PDB | External Database | Details |
|---|---|---|
| Gly -47 | - | expression tag |
| Pro -46 | - | expression tag |
| Gly -45 | - | expression tag |
| Ser -44 | - | expression tag |
| Ser -43 | - | expression tag |
| Gly -42 | - | expression tag |
| Met -41 | - | expression tag |
| Asp -40 | - | expression tag |
| Glu -39 | - | expression tag |
| Lys -38 | - | expression tag |
| Thr -37 | - | expression tag |
| Thr -36 | - | expression tag |
| Gly -35 | - | expression tag |
| Trp -34 | - | expression tag |
| Arg -33 | - | expression tag |
| Gly -32 | - | expression tag |
| Gly -31 | - | expression tag |
| His -30 | - | expression tag |
| Val -29 | - | expression tag |
| Val -28 | - | expression tag |
| Glu -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Leu -25 | - | expression tag |
| Ala -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Glu -22 | - | expression tag |
| Leu -21 | - | expression tag |
| Glu -20 | - | expression tag |
| Gln -19 | - | expression tag |
| Leu -18 | - | expression tag |
| Arg -17 | - | expression tag |
| Ala -16 | - | expression tag |
| Arg -15 | - | expression tag |
| Leu -14 | - | expression tag |
| Glu -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Pro -10 | - | expression tag |
| Gln -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Gln -7 | - | expression tag |
| Arg -6 | - | expression tag |
| Glu -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 732284.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 732546.2 |
