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7Q1E

CPAP:TUBULIN:IIH5 ALPHAREP COMPLEX

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tubulin alpha chainpolymer45150204.41UniProt (A0A6P7DY20)Ovis aries (Sheep)
2B
(B)
Tubulin beta chainpolymer44549999.91UniProt (A0A6P3TCJ9)Ovis aries (Sheep)
3C, D
(C, D)
iiH5 ALPHAREPpolymer17018866.62synthetic construct
4E
(P)
Centromere protein Jpolymer799217.61UniProt (Q9HC77)Homo sapiens (Human)CENP-J,Centrosomal P4.1-associated protein,LAG-3-associated protein,LYST-interacting protein 1
5F, H
(A, B)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.22Chemie (GTP)
6G, I
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
7J
(C)
GLYCEROLnon-polymer92.11Chemie (GOL)
8K, L, M
(A, B, C)
waterwater18.028Chemie (HOH)
Sequence modifications
P: 320 - 397 (UniProt: Q9HC77)
PDBExternal DatabaseDetails
Met 319-initiating methionine
Val 320Ala 320engineered mutation
Met 342Leu 342engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight147155.1
Non-Polymers*Number of molecules5
Total formula weight1187.1
All*Total formula weight148342.2
*Water molecules are not included.

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PDB entries from 2025-11-05

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