7Q1D
Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Aminoglycoside N(3)-acetyltransferase III | polymer | 287 | 31458.6 | 4 | UniProt (P29808) Pfam (PF02522) | Pseudomonas aeruginosa | ACC(3)-III,Aminocyclitol 3-N-acetyltransferase type III,Gentamicin-(3)-N-acetyl-transferase |
| 2 | E, F, G (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 3 | H, L, O, Q (A, B, C, D) | [[(2~{R},3~{S})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[(3~{S})-3-[2-[(1~{S})-1-[[(1~{S},2~{R},3~{R},4~{S},5~{R})-5-azanyl-3-[(4~{S},5~{R})-4-[(2~{S},3~{R},4~{R},5~{S},6~{E})-3-azanyl-6-(azanylmethylidene)-4,5-bis(oxidanyl)oxan-2-yl]oxy-5-(hydroxymethyl)-3-oxidanyl-oxolan-2-yl]oxy-2-[(2~{S},3~{R},4~{R},5~{S})-3-azanyl-6-(iminomethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-4-oxidanyl-cyclohexyl]amino]-1-oxidanyl-ethyl]sulfanylethylamino]-3-oxidanyl-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate | non-polymer | 1422.2 | 4 | Chemie (8I8) | |||
| 4 | I, J, M, N (A, B, C) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | K (B) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 6 | P (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | R, S, T, U (A, B, C, D) | water | water | 18.0 | 1143 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 291 (UniProt: P29808)
| PDB | External Database | Details |
|---|---|---|
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Val 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Arg 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| His 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 125834.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 6370.8 | |
| All* | Total formula weight | 132205.3 |
