7Q1D

Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008080	molecular_function	N-acetyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016999	biological_process	antibiotic metabolic process
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
A	0046356	biological_process	acetyl-CoA catabolic process
A	0046677	biological_process	response to antibiotic
A	0071236	biological_process	cellular response to antibiotic
A	0120225	molecular_function	coenzyme A binding
A	1901742	biological_process	2-deoxystreptamine metabolic process
B	0008080	molecular_function	N-acetyltransferase activity
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016999	biological_process	antibiotic metabolic process
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
B	0046356	biological_process	acetyl-CoA catabolic process
B	0046677	biological_process	response to antibiotic
B	0071236	biological_process	cellular response to antibiotic
B	0120225	molecular_function	coenzyme A binding
B	1901742	biological_process	2-deoxystreptamine metabolic process
C	0008080	molecular_function	N-acetyltransferase activity
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016999	biological_process	antibiotic metabolic process
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
C	0046356	biological_process	acetyl-CoA catabolic process
C	0046677	biological_process	response to antibiotic
C	0071236	biological_process	cellular response to antibiotic
C	0120225	molecular_function	coenzyme A binding
C	1901742	biological_process	2-deoxystreptamine metabolic process
D	0008080	molecular_function	N-acetyltransferase activity
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0016999	biological_process	antibiotic metabolic process
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
D	0046356	biological_process	acetyl-CoA catabolic process
D	0046677	biological_process	response to antibiotic
D	0071236	biological_process	cellular response to antibiotic
D	0120225	molecular_function	coenzyme A binding
D	1901742	biological_process	2-deoxystreptamine metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQK, ECO:0007744|PDB:7MQL, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	HIS51
A	GLU143
A	TYR166
A	THR193
A	HIS196
A	THR232
A	PHE241
B	HIS51
B	ALA52
B	SER53
B	VAL54
A	ALA52
B	LYS55
B	TYR84
B	SER124
B	VAL125
B	PHE129
B	GLU143
B	TYR166
B	THR193
B	HIS196
B	THR232
A	SER53
B	PHE241
C	HIS51
C	ALA52
C	SER53
C	VAL54
C	LYS55
C	TYR84
C	SER124
C	VAL125
C	PHE129
A	VAL54
C	GLU143
C	TYR166
C	THR193
C	HIS196
C	THR232
C	PHE241
D	HIS51
D	ALA52
D	SER53
D	VAL54
A	LYS55
D	LYS55
D	TYR84
D	SER124
D	VAL125
D	PHE129
D	GLU143
D	TYR166
D	THR193
D	HIS196
D	THR232
A	TYR84
D	PHE241
A	SER124
A	VAL125
A	PHE129

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQK, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	ASP92
A	THR191
B	ASP92
B	THR191
C	ASP92
C	THR191
D	ASP92
D	THR191

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQL, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	GLU122
A	ASP190
B	GLU122
B	ASP190
C	GLU122
C	ASP190
D	GLU122
D	ASP190

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQL

Chain	Residue	Details
A	GLY233
B	GLY233
C	GLY233
D	GLY233

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