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7Q1C

Crystal structure of Trypanosoma cruzi histone deacetylase DAC2 complexed with a hydroxamate inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Histone deacetylase DAC2polymer46750408.72Pfam (PF00850)
UniProt (by SIFTS) (A0A1B1JH81)
Trypanosoma cruzi
2C, G
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, E, H, I
(A, B)
POTASSIUM IONnon-polymer39.14Chemie (K)
4F, J
(A, B)
(E)-3-dibenzofuran-4-yl-N-oxidanyl-prop-2-enamidenon-polymer253.32Chemie (T56)
5K, L
(A, B)
waterwater18.0230Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight100817.5
Non-Polymers*Number of molecules8
Total formula weight793.7
All*Total formula weight101611.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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