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7PZD

Cryo-EM structure of the NLRP3 PYD filament

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(G, H, I, J, K...)
NACHT, LRR and PYD domains-containing protein 3polymer10812486.218UniProt (Q96P20)
Pfam (PF02758)
Homo sapiens (Human)Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1
Sequence modifications
G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X: 3 - 110 (UniProt: Q96P20)
PDBExternal DatabaseDetails
Ser 108Cys 108conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains18
Total formula weight224752.4
All*Total formula weight224752.4
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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