7PZD
Cryo-EM structure of the NLRP3 PYD filament
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (G, H, I, J, K...) | NACHT, LRR and PYD domains-containing protein 3 | polymer | 108 | 12486.2 | 18 | UniProt (Q96P20) Pfam (PF02758) | Homo sapiens (Human) | Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1 |
Sequence modifications
G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X: 3 - 110 (UniProt: Q96P20)
| PDB | External Database | Details |
|---|---|---|
| Ser 108 | Cys 108 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 224752.4 | |
| All* | Total formula weight | 224752.4 |






