7PXH
Emodepside-bound Drosophila Slo channel
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Isoform J of Calcium-activated potassium channel slowpoke | polymer | 1180 | 130919.1 | 4 | UniProt (Q03720) Pfam (PF00520) Pfam (PF03493) Pfam (PF21014) In PDB | Drosophila melanogaster (Fruit fly) | dSlo,BK channel,Maxi K channel,MaxiK |
2 | C, A, D, B | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
3 | C, A, D, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
4 | C, A, D, B | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE | non-polymer | 763.1 | 16 | Chemie (6PL) | |||
5 | C, A, D, B | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) | |||
6 | C, A | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
7 | B | (3~{S},6~{R},9~{S},12~{R},15~{S},18~{R},21~{S},24~{R})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone | non-polymer | 1119.4 | 1 | Chemie (8I2) |
Sequence modifications
A, B, C, D: 1 - 1180 (UniProt: Q03720)
PDB | External Database | Details |
---|---|---|
Asp 281 | Asn 281 | conflict |
Ile 328 | Met 328 | conflict |
Cys 332 | Ser 332 | conflict |
Asp 338 | Glu 338 | conflict |
Ile 340 | Val 340 | conflict |
Thr 342 | Ser 342 | conflict |
Arg 343 | Gly 343 | conflict |
Ala 344 | Asn 344 | conflict |
Thr 349 | Glu 349 | conflict |
Asn 352 | Arg 352 | conflict |
Lys 354 | His 354 | conflict |
Arg 356 | Lys 356 | conflict |
Gly 974 | Ser 974 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 523676.4 | |
Non-Polymers* | Number of molecules | 39 |
Total formula weight | 15528.0 | |
All* | Total formula weight | 539204.4 |