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7PX3

Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
U5 small nuclear ribonucleoprotein 200 kDa helicasepolymer1747199666.71UniProt (O75643)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF02889)
Homo sapiens (Human)Activating signal cointegrator 1 complex subunit 3-like 1,BRR2 homolog,U5 snRNP-specific 200 kDa protein,U5-200KD
2B
(J)
Pre-mRNA-processing-splicing factor 8polymer26330133.21UniProt (Q6P2Q9)
Pfam (PF01398)
Pfam (PF08084)
Homo sapiens (Human)220 kDa U5 snRNP-specific protein,PRP8 homolog,Splicing factor Prp8,p220
3C
(T)
Protein TSSC4polymer32934366.51UniProt (Q9Y5U2)
Pfam (PF15264)
Homo sapiens (Human)Tumor-suppressing STF cDNA 4 protein,Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein
Sequence modifications
B: 394 - 2136 (UniProt: O75643)
PDBExternal DatabaseDetails
Gly 390-expression tag
Ala 391-expression tag
Glu 392-expression tag
Phe 393-expression tag
J: 2064 - 2320 (UniProt: Q6P2Q9)
PDBExternal DatabaseDetails
Gly 2058-expression tag
Pro 2059-expression tag
Leu 2060-expression tag
Gly 2061-expression tag
Ser 2062-expression tag
Met 2063-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight264166.3
All*Total formula weight264166.3
*Water molecules are not included.

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PDB entries from 2025-07-09

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