7PWO
Cryo-EM structure of Giardia lamblia ribosome at 2.75 A resolution
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T1) | Ribosomal protein S19e | polymer | 139 | 15463.9 | 1 | UniProt (A0A644F964) Pfam (PF01090) | Giardia lamblia ATCC 50803 | |
| 2 | B (N1) | Ribosomal protein S13 | polymer | 154 | 17627.9 | 1 | UniProt (A8BE02) Pfam (PF08069) Pfam (PF00312) | Giardia lamblia ATCC 50803 | |
| 3 | C (J1) | Ribosomal protein S9 | polymer | 189 | 21699.3 | 1 | UniProt (A8BKS8) Pfam (PF00163) Pfam (PF01479) | Giardia lamblia ATCC 50803 | |
| 4 | D (D1) | Ribosomal protein S3 | polymer | 217 | 24779.1 | 1 | UniProt (A8B8Z2) Pfam (PF00189) | Giardia lamblia ATCC 50803 | |
| 5 | E (X1) | Ribosomal protein S23 | polymer | 143 | 15897.8 | 1 | UniProt (A8BS96) Pfam (PF00164) | Giardia lamblia ATCC 50803 | |
| 6 | F (S1) | Ribosomal protein S18 | polymer | 154 | 17510.3 | 1 | UniProt (A8BZ58) Pfam (PF00416) | Giardia lamblia ATCC 50803 | |
| 7 | G (Q1) | Ribosomal protein S16 | polymer | 158 | 17634.6 | 1 | UniProt (A8BKC6) Pfam (PF00380) | Giardia lamblia ATCC 50803 | |
| 8 | H (C1) | Ribosomal protein S2 | polymer | 242 | 26765.7 | 1 | UniProt (A8BMZ1) Pfam (PF00333) Pfam (PF03719) | Giardia lamblia ATCC 50803 | |
| 9 | I (B1) | 40S ribosomal protein S3a | polymer | 248 | 28413.1 | 1 | UniProt (A8BS79) | Giardia lamblia ATCC 50803 | |
| 10 | J (b1) | Ribosomal protein S27 | polymer | 124 | 14117.3 | 1 | UniProt (A8BJL1) | Giardia lamblia ATCC 50803 | |
| 11 | K (a1) | 40S ribosomal protein S26 | polymer | 109 | 12791.0 | 1 | UniProt (A8BQZ7) Pfam (PF01283) | Giardia lamblia ATCC 50803 | |
| 12 | L (V1) | 40S ribosomal protein S21 | polymer | 89 | 9686.1 | 1 | UniProt (A8B484) Pfam (PF01249) | Giardia lamblia ATCC 50803 | |
| 13 | M (R1) | Ribosomal protein S17 | polymer | 137 | 15757.4 | 1 | UniProt (A8BRG5) Pfam (PF00833) | Giardia lamblia ATCC 50803 | |
| 14 | N (K1) | Ribosomal protein S10B | polymer | 134 | 15406.6 | 1 | UniProt (A8BRX3) Pfam (PF03501) | Giardia lamblia ATCC 50803 | |
| 15 | O (I1) | 40S ribosomal protein S8 | polymer | 174 | 19451.6 | 1 | UniProt (A8B252) Pfam (PF01201) | Giardia lamblia ATCC 50803 | |
| 16 | P (e1) | 40S ribosomal protein S30 | polymer | 69 | 7932.4 | 1 | UniProt (A0A644F843) Pfam (PF04758) | Giardia lamblia ATCC 50803 | |
| 17 | Q (H1) | 40S ribosomal protein S7 | polymer | 190 | 21786.5 | 1 | UniProt (A8BT38) Pfam (PF01251) | Giardia lamblia ATCC 50803 | |
| 18 | R (n1) | Ribosomal protein eL41 | polymer | 41 | 5194.3 | 1 | UniProt (V6TX21) | Giardia lamblia ATCC 50803 | |
| 19 | S (c1) | Ribosomal protein S28 | polymer | 64 | 7358.6 | 1 | UniProt (A8B4F3) Pfam (PF01200) | Giardia lamblia ATCC 50803 | |
| 20 | T (O1) | Ribosomal protein S14 | polymer | 145 | 15756.0 | 1 | UniProt (E2RU83) Pfam (PF00411) | Giardia lamblia ATCC 50803 | |
| 21 | U (W1) | Ribosomal protein S15A | polymer | 130 | 14770.3 | 1 | UniProt (E2RU77) Pfam (PF00410) | Giardia lamblia ATCC 50803 | |
| 22 | V (E1) | 40S ribosomal protein S4 | polymer | 268 | 30464.8 | 1 | UniProt (A8BFE3) Pfam (PF08071) Pfam (PF00900) Pfam (PF16121) | Giardia lamblia ATCC 50803 | |
| 23 | W (L1) | SSU ribosomal protein S17P | polymer | 199 | 23245.0 | 1 | UniProt (V6TVJ7) | Giardia lamblia ATCC 50803 | |
| 24 | X (U1) | Ribosomal protein S20 | polymer | 126 | 14073.2 | 1 | UniProt (A8B4G0) Pfam (PF00338) | Giardia lamblia ATCC 50803 | |
| 25 | Y (1) | rRNA 28S | polymer | 2707 | 878238.5 | 1 | Giardia lamblia ATCC 50803 | ||
| 26 | Z (3) | rRNA 5S | polymer | 120 | 38671.0 | 1 | Giardia lamblia ATCC 50803 | ||
| 27 | AA (42) | rRNA 5.8S | polymer | 139 | 44972.0 | 1 | GenBank (9351) | Giardia lamblia ATCC 50803 | |
| 28 | BA (A2) | Ribosomal protein L2 | polymer | 251 | 27090.5 | 1 | UniProt (E2RTN4) Pfam (PF00181) Pfam (PF03947) | Giardia lamblia ATCC 50803 | Ribosomal protein L8 |
| 29 | CA (B2) | Ribosomal protein L3 | polymer | 379 | 42715.5 | 1 | UniProt (A8BRZ3) Pfam (PF00297) | Giardia lamblia ATCC 50803 | |
| 30 | DA (C2) | Ribosomal protein L4 | polymer | 316 | 35048.7 | 1 | UniProt (A8B7H8) Pfam (PF00573) Pfam (PF14374) | Giardia lamblia ATCC 50803 | |
| 31 | EA (D2) | Ribosomal protein L5 | polymer | 297 | 33961.4 | 1 | UniProt (E2RU47) Pfam (PF14204) Pfam (PF17144) | Giardia lamblia ATCC 50803 | |
| 32 | FA (F2) | Ribosomal protein L7 | polymer | 235 | 27103.4 | 1 | UniProt (A8BRY6) Pfam (PF00327) | Giardia lamblia ATCC 50803 | |
| 33 | GA (G2) | 60S ribosomal protein L7a | polymer | 225 | 25427.7 | 1 | UniProt (A8BLL7) Pfam (PF01248) | Giardia lamblia ATCC 50803 | |
| 34 | HA (H2) | Ribosomal protein L6 | polymer | 185 | 20889.4 | 1 | UniProt (A8BNT5) Pfam (PF00347) | Giardia lamblia ATCC 50803 | Ribosomal protein L9 |
| 35 | IA (I2) | Ribosomal protein L10 | polymer | 210 | 24283.2 | 1 | UniProt (A8BM86) Pfam (PF00252) | Giardia lamblia ATCC 50803 | |
| 36 | JA (J2) | Ribosomal protein L11 | polymer | 173 | 19767.7 | 1 | UniProt (A8BI95) Pfam (PF00281) Pfam (PF00673) | Giardia lamblia ATCC 50803 | |
| 37 | KA (L2) | 60S ribosomal protein L13 | polymer | 234 | 26640.3 | 1 | UniProt (A8B6M8) | Giardia lamblia ATCC 50803 | |
| 38 | LA (M2) | Ribosomal protein L14 | polymer | 131 | 14785.5 | 1 | UniProt (A8B4F8) Pfam (PF01929) | Giardia lamblia ATCC 50803 | |
| 39 | MA (N2) | Ribosomal protein L15 | polymer | 204 | 24353.7 | 1 | UniProt (A8B8Z6) Pfam (PF00827) | Giardia lamblia ATCC 50803 | |
| 40 | NA (O2) | Ribosomal protein L13a | polymer | 197 | 22921.9 | 1 | UniProt (A8BU75) Pfam (PF00572) | Giardia lamblia ATCC 50803 | |
| 41 | OA (P2) | Ribosomal protein L17 | polymer | 164 | 18722.8 | 1 | UniProt (A8BE76) Pfam (PF00237) | Giardia lamblia ATCC 50803 | |
| 42 | PA (Q2) | Ribosomal protein L18 | polymer | 179 | 20207.8 | 1 | UniProt (A8B4T7) Pfam (PF17135) | Giardia lamblia ATCC 50803 | |
| 43 | QA (R2) | Ribosomal protein L19 | polymer | 196 | 23199.2 | 1 | UniProt (A8BH61) Pfam (PF01280) Pfam (PF25476) | Giardia lamblia ATCC 50803 | |
| 44 | RA (S2) | 60S ribosomal protein L18a | polymer | 173 | 20624.9 | 1 | UniProt (A8BT04) | Giardia lamblia ATCC 50803 | |
| 45 | SA (T2) | Ribosomal protein L21 | polymer | 159 | 18296.4 | 1 | UniProt (A8B2Q4) Pfam (PF01157) | Giardia lamblia ATCC 50803 | |
| 46 | TA (U2) | Ribosomal protein eL22 | polymer | 171 | 19942.4 | 1 | UniProt (A8BW84) | Giardia lamblia ATCC 50803 | |
| 47 | UA (V2) | Ribosomal protein L23 | polymer | 142 | 15450.0 | 1 | UniProt (A8BS37) Pfam (PF00238) | Giardia lamblia ATCC 50803 | |
| 48 | VA (X2) | Ribosomal protein L23A | polymer | 141 | 16053.9 | 1 | UniProt (A8BMP6) Pfam (PF03939) Pfam (PF00276) | Giardia lamblia ATCC 50803 | |
| 49 | WA (Y2) | Ribosomal protein L26 | polymer | 135 | 15621.4 | 1 | UniProt (A8BFT3) Pfam (PF16906) | Giardia lamblia ATCC 50803 | |
| 50 | XA (Z2) | 60S ribosomal protein L27 | polymer | 135 | 15374.9 | 1 | UniProt (A8B1T3) Pfam (PF00467) Pfam (PF01777) | Giardia lamblia ATCC 50803 | |
| 51 | YA (a2) | Ribosomal protein L27a | polymer | 149 | 17167.0 | 1 | UniProt (A8BZ78) Pfam (PF00828) | Giardia lamblia ATCC 50803 | |
| 52 | ZA (b2) | 60S ribosomal protein L29 | polymer | 62 | 7363.6 | 1 | UniProt (A8BYY2) Pfam (PF01779) | Giardia lamblia ATCC 50803 | |
| 53 | AB (c2) | Ribosomal protein L30 | polymer | 109 | 11698.6 | 1 | UniProt (A8B5N7) Pfam (PF01248) | Giardia lamblia ATCC 50803 | |
| 54 | BB (d2) | Ribosomal protein L31B | polymer | 106 | 12184.1 | 1 | UniProt (A8BMP3) Pfam (PF01198) | Giardia lamblia ATCC 50803 | Ribosomal protein L31e |
| 55 | CB (e2) | Ribosomal protein L32 | polymer | 136 | 15986.0 | 1 | UniProt (A8BMD9) Pfam (PF01655) | Giardia lamblia ATCC 50803 | |
| 56 | DB (f2) | Ribosomal protein L35a | polymer | 123 | 13913.1 | 1 | UniProt (A8BKK5) Pfam (PF01247) | Giardia lamblia ATCC 50803 | |
| 57 | EB (g2) | Ribosomal protein L34 | polymer | 120 | 13528.8 | 1 | UniProt (A8BMF7) Pfam (PF01199) | Giardia lamblia ATCC 50803 | |
| 58 | FB (h2) | Ribosomal protein L35 | polymer | 124 | 14292.2 | 1 | UniProt (A8BRG7) | Giardia lamblia ATCC 50803 | |
| 59 | GB (i2) | Ribosomal protein L36-1 | polymer | 90 | 10586.7 | 1 | UniProt (A8BYA6) Pfam (PF01158) | Giardia lamblia ATCC 50803 | Ribosomal protein L36e |
| 60 | HB (j2) | Ribosomal protein L37 | polymer | 89 | 10329.0 | 1 | UniProt (A8BLV7) Pfam (PF01907) | Giardia lamblia ATCC 50803 | |
| 61 | IB (k2) | Ribosomal L38e | polymer | 77 | 8605.1 | 1 | UniProt (A8B481) Pfam (PF01781) | Giardia lamblia ATCC 50803 | |
| 62 | JB (l2) | Ribosomal protein L39 | polymer | 51 | 6353.7 | 1 | UniProt (A0A644EZB9) Pfam (PF00832) | Giardia lamblia ATCC 50803 | |
| 63 | KB (m2) | Ubiquitin/Ribosomal protein L40e | polymer | 127 | 14343.7 | 1 | UniProt (A8BXE1) Pfam (PF00240) Pfam (PF01020) | Giardia lamblia ATCC 50803 | Ubiquitin/ribosomal protein CEP52 |
| 64 | LB (o2) | Ribosomal protein L44 | polymer | 106 | 12311.7 | 1 | UniProt (A8BQU8) Pfam (PF00935) | Giardia lamblia ATCC 50803 | |
| 65 | MB (p2) | Ribosomal protein L37a | polymer | 94 | 10508.4 | 1 | UniProt (A8BN26) Pfam (PF01780) | Giardia lamblia ATCC 50803 | |
| 66 | NB (w2) | E-site tRNA | polymer | 14 | 4459.8 | 1 | Giardia lamblia ATCC 50803 | ||
| 67 | OB (W2) | Ribosomal protein L24A | polymer | 102 | 12005.2 | 1 | UniProt (A8BRH7) Pfam (PF01246) | Giardia lamblia ATCC 50803 | |
| 68 | PB (E) | P-site tRNA | polymer | 3 | 894.6 | 1 | Giardia lamblia ATCC 50803 | ||
| 69 | QB (d1) | Ribosomal protein S29A | polymer | 137 | 15499.8 | 1 | UniProt (A8B7H6) | Giardia lamblia ATCC 50803 | |
| 70 | RB (F1) | Ribosomal protein S5 | polymer | 190 | 21058.3 | 1 | UniProt (A8BZD3) Pfam (PF00177) | Giardia lamblia ATCC 50803 | |
| 71 | SB (Y1) | Ribosomal protein S24 | polymer | 132 | 14872.6 | 1 | UniProt (A8B593) Pfam (PF01282) | Giardia lamblia ATCC 50803 | |
| 72 | TB (G1) | 40S ribosomal protein S6 | polymer | 248 | 28084.1 | 1 | UniProt (A8B6L8) Pfam (PF01092) | Giardia lamblia ATCC 50803 | |
| 73 | UB (2) | rRNA 18S | polymer | 1452 | 471124.5 | 1 | Giardia lamblia ATCC 50803 | ||
| 74 | VB (A1) | 40S ribosomal protein SA | polymer | 245 | 28101.8 | 1 | UniProt (A8BE86) | Giardia lamblia ATCC 50803 | |
| 75 | AC, AD, AG, AH, AI... (X1, 1, B2, 2, S1...) | POTASSIUM ION | non-polymer | 39.1 | 455 | Chemie (K) | |||
| 76 | AE, AF, AX, BE, BF... (1, 2, C2, F2, P2...) | MAGNESIUM ION | non-polymer | 24.3 | 101 | Chemie (MG) |
Sequence modifications
L1: 2 - 200 (UniProt: V6TVJ7)
| PDB | External Database | Details |
|---|---|---|
| Ser 12 | Gly 35 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 74 |
| Total formula weight | 2679219.4 | |
| Non-Polymers* | Number of molecules | 556 |
| Total formula weight | 20244.4 | |
| All* | Total formula weight | 2699463.8 |
