7PW0
Crystal structure of the c-Src SH3 domain N112G-N113Y-T114N-E115H mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Isoform 1 of Proto-oncogene tyrosine-protein kinase Src | polymer | 60 | 6763.4 | 8 | UniProt (P00523-1) Pfam (PF00018) UniProt (by SIFTS) (P00523) In PDB | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | water | water | 18.0 | 386 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 82 - 141 (UniProt: P00523-1)
| PDB | External Database | Details |
|---|---|---|
| Gly 112 | Asn 112 | engineered mutation |
| Tyr 113 | Asn 113 | engineered mutation |
| Asn 114 | Thr 114 | engineered mutation |
| His 115 | Glu 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 54106.9 | |
| All* | Total formula weight | 54106.9 |
