7PT4
Actinobacterial 2-hydroxyacyl-CoA lyase (AcHACL) structure in complex with a covalently bound reaction intermediate as well as products formyl-CoA and acetone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2-hydroxyacyl-CoA lyase | polymer | 612 | 65362.2 | 2 | Pfam (PF02776) Pfam (PF00205) Pfam (PF02775) UniProt (by SIFTS) (P0DUV9) | Actinomycetospora chiangmaiensis DSM 45062 | |
| 2 | C (A) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 1 | Chemie (TPP) | |||
| 3 | AA, D, E, F, G... (B, A) | SULFATE ION | non-polymer | 96.1 | 19 | Chemie (SO4) | |||
| 4 | P (A) | ACETONE | non-polymer | 58.1 | 1 | Chemie (ACN) | |||
| 5 | Q (A) | S-{(9R,13S,15R)-17-[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]-9,13,15-TRIHYDROXY-10,10-DIMETHYL-13,15-DIOXIDO-4,8-DIOXO-12,14,16-TRIOXA-3,7-DIAZA-13,15-DIPHOSPHAHEPTADEC-1-YL} THIOFORMATE | non-polymer | 795.5 | 1 | Chemie (FYN) | |||
| 6 | BA, CA, R, S (B, A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 7 | T (B) | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1R,11R,15S,17R)-19-[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]-1,11,15,17-TETRAHYDROXY-12,12-DIMETHYL-15,17-DIOXIDO-6,10-DIOXO-14,16,18-TRIOXA-2-THIA-5,9-DIAZA-15,17-DIPHOSPHANONADEC-1-YL}-5-(2-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM | non-polymer | 1220.9 | 1 | Chemie (OXT) | |||
| 8 | DA, EA (A, B) | water | water | 18.0 | 1049 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 130724.3 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 4422.2 | |
| All* | Total formula weight | 135146.5 |
