7PPG
CRYSTAL STRUCTURE OF NAMPT IN COMPLEX WITH COMPOUND 9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Nicotinamide phosphoribosyltransferase | polymer | 492 | 55652.0 | 4 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) In PDB | Homo sapiens (Human) | NAmPRTase,Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin |
| 2 | A, B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
| 3 | A, B, C, D | N-[4-[(4R)-1-cyclopentyl-4-methyl-6-oxidanylidene-4,5-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide | non-polymer | 417.5 | 4 | Chemie (7YX) | |||
| 4 | A, B, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 1316 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 491 (UniProt: P43490)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 222608.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2583.1 | |
| All* | Total formula weight | 225191.0 |
