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7POX

TNKS2 in complex with OM-1700, treated with H2O2

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(AAA, BBB)
Poly [ADP-ribose] polymerase tankyrase-2polymer21924828.12UniProt (Q9H2K2)
Pfam (PF00644)
Homo sapiens (Human)ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
2C, D
(AAA, BBB)
N-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]pyridine-2-carboxamidenon-polymer458.52Chemie (N8K)
3E, F
(AAA, BBB)
waterwater18.032Chemie (HOH)
Sequence modifications
AAA, BBB: 946 - 1162 (UniProt: Q9H2K2)
PDBExternal DatabaseDetails
Ser 944-expression tag
Met 945-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight49656.2
Non-Polymers*Number of molecules2
Total formula weight917.0
All*Total formula weight50573.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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