7PLK
Crystal structure bovine Hsc70(aa1-554)E213A/D214A in complex with nicotinic-acid-derivative
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Heat shock cognate 71 kDa protein | polymer | 554 | 60978.9 | 1 | UniProt (P19120) Pfam (PF00012) In PDB | Bos taurus (Bovine) | Heat shock 70 kDa protein 8 |
2 | A | 5-pyrrol-1-ylpyridine-3-carboxylic acid | non-polymer | 188.2 | 1 | Chemie (7UE) | |||
3 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
4 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 1 - 554 (UniProt: P19120)
PDB | External Database | Details |
---|---|---|
Ala 213 | Glu 213 | engineered mutation |
Ala 214 | Asp 214 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 60978.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 557.7 | |
All* | Total formula weight | 61536.5 |