7PEP

Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (AAA, BBB, CCC, DDD)	Beta-lactamase	polymer	260	30254.1	4	UniProt (Q6XEC0) Pfam (PF00905)	Klebsiella pneumoniae
2	E, G, M, O (AAA, BBB, CCC, DDD)	(2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid	non-polymer		317.4	4	Chemie (HIW)
3	F, H, I, J, N... (AAA, BBB, CCC, DDD)	BROMIDE ION	non-polymer		79.9	6	Chemie (BR)
4	K, L (CCC)	1-BUTANOL	non-polymer		74.1	2	Chemie (1BO)
5	Q, R, S, T (AAA, BBB, CCC, DDD)	water	water		18.0	878	Chemie (HOH)

Sequence modifications

AAA, BBB, CCC, DDD: 23 - 265 (UniProt: Q6XEC0)

PDB	External Database	Details
Met 6	-	initiating methionine
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 13	-	expression tag
Ala 14	-	expression tag
Gly 15	-	expression tag
Glu 16	-	expression tag
Asn 17	-	expression tag
Leu 18	-	expression tag
Tyr 19	-	expression tag
Phe 20	-	expression tag
Gln 21	-	expression tag
Gly 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	121016.5
Non-Polymers*	Number of molecules	12
	Total formula weight	1897.1
All*	Total formula weight	122913.6

*Water molecules are not included.