7PCJ
X-ray structure of CypA-C52AK125C/CsA/aromatic foldamer complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | Peptidyl-prolyl cis-trans isomerase A | polymer | 165 | 18010.5 | 2 | UniProt (P62937) Pfam (PF00160) | Homo sapiens (human) | PPIase A,Cyclophilin A,Cyclosporin A-binding protein,Rotamase A |
| 2 | B, D (B, E) | Cyclosporin A | polymer | 11 | 1220.6 | 2 | BIRD (PRD_000142) | Tolypocladium inflatum | |
| 3 | E, F (F, C) | Aromatic foldamer | polymer | 7 | 1495.6 | 2 | synthetic construct | ||
| 4 | G, H, I, J, K... (A, B, D, E, F...) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, D: 3 - 167 (UniProt: P62937)
| PDB | External Database | Details |
|---|---|---|
| Cys 127 | Lys 125 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 41453.4 | |
| All* | Total formula weight | 41453.4 |
