7PC8

The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ-binding motif of RSK1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Gamma-1-syntrophin,Annexin A2	polymer	414	46770.4	2	UniProt (Q9NSN8) UniProt (P07355) Pfam (PF00595) Pfam (PF00191) In PDB	Homo sapiens (Human)	G1SYN,Syntrophin-4,SYN4,Annexin II,Annexin-2,Calpactin I heavy chain,Calpactin-1 heavy chain,Chromobindin-8,Lipocortin II,Placental anticoagulant protein IV,PAP-IV,Protein I,p36
2	C, D	Ribosomal protein S6 kinase alpha-1	polymer	10	1215.5	2	UniProt (Q15418) In PDB	Homo sapiens	S6K-alpha-1,90 kDa ribosomal protein S6 kinase 1,p90-RSK 1,p90RSK1,p90S6K,MAP kinase-activated protein kinase 1a,MAPK-activated protein kinase 1a,MAPKAP kinase 1a,MAPKAPK-1a,Ribosomal S6 kinase 1,RSK-1
3	A, B	CALCIUM ION	non-polymer		40.1	9	Chemie (CA)
4	A, B	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
5		water	water		18.0	221	Chemie (HOH)

Sequence modifications

A, B: 54 - 143 (UniProt: Q9NSN8)

PDB	External Database	Details
Gly 49	-	expression tag
Ser 50	-	expression tag
His 51	-	expression tag
Met 52	-	expression tag
Gly 53	-	expression tag
Gly 144	-	linker

A, B: 145 - 462 (UniProt: P07355)

PDB	External Database	Details
Glu 189	Ala 66	conflict

C, D: 180 - 189 (UniProt: Q15418)

PDB	External Database	Details
Glu 186	Ser 732	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	95971.7
Non-Polymers*	Number of molecules	15
	Total formula weight	913.3
All*	Total formula weight	96885.0

*Water molecules are not included.