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7PC3

The second PDZ domain of DLG1 complexed with the PDZ-binding motif of HTLV1-TAX1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Disks large homolog 1,Annexin A2polymer41746970.61UniProt (Q12959)
UniProt (P07355)
Pfam (PF00595)
Pfam (PF00191)
Homo sapiens (Human)Synapse-associated protein 97,SAP-97,SAP97,hDlg,Annexin II,Annexin-2,Calpactin I heavy chain,Calpactin-1 heavy chain,Chromobindin-8,Lipocortin II,Placental anticoagulant protein IV,PAP-IV,Protein I,p36
2B
(C)
Protein Tax-1polymer101264.41UniProt (P03409)HTLV-1 subtype AProtein X-LOR,Protein PX,Trans-activating transcriptional regulatory protein of HTLV-1
3C, D, E, F
(A)
CALCIUM IONnon-polymer40.14Chemie (CA)
4G, H, I, J
(A)
GLYCEROLnon-polymer92.14Chemie (GOL)
5K
(C)
SULFATE IONnon-polymer96.11Chemie (SO4)
6L, M
(A, C)
waterwater18.0397Chemie (HOH)
Sequence modifications
A: 314 - 413 (UniProt: Q12959)
PDBExternal DatabaseDetails
Gly 309-expression tag
Ser 310-expression tag
His 311-expression tag
Met 312-expression tag
Gly 313-expression tag
Ser 414-linker
A: 415 - 725 (UniProt: P07355)
PDBExternal DatabaseDetails
Glu 452Ala 66conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight48234.9
Non-Polymers*Number of molecules9
Total formula weight624.8
All*Total formula weight48859.7
*Water molecules are not included.

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PDB entries from 2024-10-30

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