7PBC
Crystal structure of engineered TCR (796) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (CCC) | MHC class I antigen | polymer | 277 | 32082.5 | 1 | UniProt (Q861F7) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B (DDD) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (AAA) | T-cell receptor (TRAV/TRAC) | polymer | 206 | 22818.1 | 1 | Homo sapiens | ||
| 4 | D (BBB) | T-cell receptor (TRBV/TRBC) | polymer | 241 | 27171.4 | 1 | Homo sapiens | ||
| 5 | E (EEE) | Melanoma-associated antigen 10 | polymer | 9 | 1035.2 | 1 | UniProt (P43363) | Homo sapiens | Cancer/testis antigen 1.10,CT1.10,MAGE-10 antigen |
| 6 | F, G, H (CCC) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | I (BBB) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | J, K, L, M, N (CCC, DDD, AAA, BBB, EEE) | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence modifications
CCC: 2 - 277 (UniProt: Q861F7)
DDD: 2 - 100 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 94986.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 311.7 | |
| All* | Total formula weight | 95298.2 |
