7P70

The PDZ-domain of SNTB1 complexed with the PDZ-binding motif of HPV35-E6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	Protein E6	polymer	13	1536.6	1	UniProt (P27228)	Human papillomavirus 35
2	B (A)	Beta-1-syntrophin,Annexin A2	polymer	414	46699.4	1	UniProt (Q13884) UniProt (P07355) Pfam (PF00595) Pfam (PF00191)	Homo sapiens (Human)	59 kDa dystrophin-associated protein A1 basic component 1,DAPA1B,BSYN2,Syntrophin-2,Tax interaction protein 43,TIP-43,Annexin II,Annexin-2,Calpactin I heavy chain,Calpactin-1 heavy chain,Chromobindin-8,Lipocortin II,Placental anticoagulant protein IV,PAP-IV,Protein I,p36
3	C, D, E, F, G (A)	CALCIUM ION	non-polymer		40.1	5	Chemie (CA)
4	H, I (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	J, K (C, A)	water	water		18.0	253	Chemie (HOH)

Sequence modifications

C: 141 - 149 (UniProt: P27228)

PDB	External Database	Details
Thr 137	-	linker
Asp 138	-	linker
Asp 139	-	linker
Ser 140	-	linker

A: 107 - 196 (UniProt: Q13884)

PDB	External Database	Details
Gly 102	-	expression tag
Ser 103	-	expression tag
His 104	-	expression tag
Met 105	-	expression tag
Gly 106	-	expression tag
Gly 197	-	linker

A: 198 - 515 (UniProt: P07355)

PDB	External Database	Details
Glu 242	Ala 66	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48236.0
Non-Polymers*	Number of molecules	7
	Total formula weight	384.6
All*	Total formula weight	48620.6

*Water molecules are not included.