7P6P

ROCK2 IN COMPLEX WITH COMPOUND 17

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Rho-associated protein kinase 2	polymer	399	45700.9	4	UniProt (O75116) Pfam (PF00069)	Homo sapiens (Human)	Rho kinase 2,Rho-associated,coiled-coil-containing protein kinase 2,coiled-coil-containing protein kinase II,ROCK-II,p164 ROCK-2
2	E, G, I, J (A, B, C, D)	~{N}-[(1~{R})-1-(3-methoxyphenyl)ethyl]-4-pyridin-4-yl-cyclohexane-1-carboxamide	non-polymer		338.4	4	Chemie (5YV)
3	F (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	H, K (B, D)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
5	L, M, N, O (A, B, C, D)	water	water		18.0	39	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	182803.7
Non-Polymers*	Number of molecules	7
	Total formula weight	1779.7
All*	Total formula weight	184583.4

*Water molecules are not included.