7P54

Cryo-EM structure of human TTYH2 in GDN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein tweety homolog 2	polymer	541	59573.9	2	UniProt (Q9BSA4) Pfam (PF04906)	Homo sapiens (Human)	hTTY2
2	C, D, E, F (C, D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
3	G, H, I, J (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

A, B: 2 - 534 (UniProt: Q9BSA4)

PDB	External Database	Details
Ser 1	-	expression tag
Ala 535	-	expression tag
Leu 536	-	expression tag
Glu 537	-	expression tag
Val 538	-	expression tag
Leu 539	-	expression tag
Phe 540	-	expression tag
Gln 541	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119147.8
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	121730.2

*Water molecules are not included.