7P4S
BROMODOMAIN OF HUMAN TAF1 (2) WITH naphthyridinone compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 2a of Transcription initiation factor TFIID subunit 1 | polymer | 137 | 15852.8 | 1 | UniProt (P21675) Pfam (PF00439) | Homo sapiens (Human) | Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAF(II)250,TAFII-250,TAFII250 |
| 2 | B, C (A) | 8-[[1-(3-azanylpropyl)piperidin-4-yl]amino]-5-[5-(hydroxymethyl)pyridin-3-yl]-3-methyl-1~{H}-1,7-naphthyridin-2-one | non-polymer | 422.5 | 2 | Chemie (5LV) | |||
| 3 | D (A) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A: 1501 - 1635 (UniProt: P21675)
| PDB | External Database | Details |
|---|---|---|
| Gly 1499 | - | expression tag |
| Met 1500 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15852.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 845.0 | |
| All* | Total formula weight | 16697.8 |
