7P4E
Crystal structure of PPARgamma in complex with compound FL217
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 277 | 31667.8 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B (A) | ~{N}-[[4-(cyclopropylsulfonylamino)-2-(trifluoromethyl)phenyl]methyl]-1-[(3-fluorophenyl)methyl]indole-5-carboxamide | non-polymer | 545.5 | 1 | Chemie (5IV) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D, E, F, G, H... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | J (A) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Ser 201 | - | expression tag |
| Met 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31667.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1014.0 | |
| All* | Total formula weight | 32681.8 |
