7P41

Crystal Structure of human mARC1 A165T Variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	D	Mitochondrial amidoxime-reducing component 1,Endolysin,Mitochondrial amidoxime-reducing component 1	polymer	448	50546.1	1	UniProt (Q5VT66) UniProt (D9IEF7) Pfam (PF03476) Pfam (PF00959) Pfam (PF03473) In PDB	Homo sapiens (Human)	mARC1,Molybdenum cofactor sulfurase C-terminal domain-containing protein 1,MOSC domain-containing protein 1,Moco sulfurase C-terminal domain-containing protein 1,Lysis protein,Lysozyme,Muramidase,mARC1,Molybdenum cofactor sulfurase C-terminal domain-containing protein 1,MOSC domain-containing protein 1,Moco sulfurase C-terminal domain-containing protein 1
2	D	oxidanyl(oxidanylidene)molybdenum	non-polymer		128.9	1	Chemie (EFK)
3	D	PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER	non-polymer		395.4	1	Chemie (MTE)
4	D	2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		282.3	1	Chemie (B3P)
5	D	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6		water	water		18.0	574	Chemie (HOH)

Sequence modifications

D: 53 - 128 (UniProt: Q5VT66)

PDB	External Database	Details
Met 48	-	initiating methionine
Arg 49	-	expression tag
Gly 50	-	expression tag
Ser 51	-	expression tag
Met 52	-	expression tag

D: 129 - 287 (UniProt: D9IEF7)
D: 288 - 495 (UniProt: Q5VT66)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	50546.1
Non-Polymers*	Number of molecules	4
	Total formula weight	842.1
All*	Total formula weight	51388.2

*Water molecules are not included.