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7P1L

The MARK3 Kinase Domain Bound To AA-CS-1-008

Replaces:  7O94
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BMAP/microtubule affinity-regulating kinase 3polymer32637698.62UniProt (P27448)
Pfam (PF00069)
Pfam (PF00627)
In PDB
Homo sapiens (Human)C-TAK1,cTAK1,Cdc25C-associated protein kinase 1,ELKL motif kinase 2,EMK-2,Protein kinase STK10,Ser/Thr protein kinase PAR-1,Par-1a,Serine/threonine-protein kinase p78
2A, B5-Bromo-4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-(morpholin-4-ylmethyl)phenyl]pyrimidine-2,4-diaminenon-polymer458.42Chemie (V5E)
3A, B1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4waterwater18.0103Chemie (HOH)
Sequence modifications
A, B: 48 - 366 (UniProt: P27448)
PDBExternal DatabaseDetails
Ala 367-expression tag
Glu 368-expression tag
Asn 369-expression tag
Leu 370-expression tag
Tyr 371-expression tag
Phe 372-expression tag
Gln 373-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight75397.2
Non-Polymers*Number of molecules5
Total formula weight1102.9
All*Total formula weight76500.1
*Water molecules are not included.

220113

PDB entries from 2024-05-22

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