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7P06

Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in outward-facing conformation with ADP-orthovanadate/ATP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Pleiotropic ABC efflux transporter of multiple drugspolymer1511170617.31UniProt (P33302)
Pfam (PF14510)
Pfam (PF00005)
Pfam (PF01061)
Pfam (PF06422)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Pleiotropic drug resistance protein 5,Suppressor of toxicity of sporidesmin
2B
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
ADP ORTHOVANADATEnon-polymer544.21Chemie (AOV)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight170617.3
Non-Polymers*Number of molecules3
Total formula weight1075.6
All*Total formula weight171692.9
*Water molecules are not included.

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PDB entries from 2025-12-24

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