7OZM
Crystal Structure of mtbMGL K74A (Closed Cap Conformation)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Monoacylglycerol lipase | polymer | 307 | 33618.0 | 1 | UniProt (O07427) Pfam (PF12146) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | MGL |
| 2 | B (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 3 | C (A) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 1 - 279 (UniProt: O07427)
| PDB | External Database | Details |
|---|---|---|
| Met -27 | - | initiating methionine |
| Ser -26 | - | expression tag |
| Tyr -25 | - | expression tag |
| Tyr -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Ile -14 | - | expression tag |
| Pro -13 | - | expression tag |
| Thr -12 | - | expression tag |
| Thr -11 | - | expression tag |
| Glu -10 | - | expression tag |
| Asn -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Tyr -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 74 | Lys 74 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33618.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 60.1 | |
| All* | Total formula weight | 33678.1 |
