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7OYC

Cryo-EM structure of the Xenopus egg 80S ribosome

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(11)
Eukaryotic translation initiation factor 5Apolymer15416813.31UniProt (Q7ZXG3)
Pfam (PF21485)
Pfam (PF01287)
Xenopus laevis (African clawed frog)eIF-5A
2B
(22)
18S rRNApolymer1826588678.01GenBank (X04025.1)Xenopus laevis (African clawed frog)
3C
(51)
28S rRNApolymer41151333067.31GenBank (X59734.1)Xenopus laevis (African clawed frog)
4D
(71)
5S rRNApolymer12038683.01GenBank (M10635.1)Xenopus laevis (African clawed frog)
5E
(81)
5.8S rRNApolymer15650198.71GenBank (X02995.1)Xenopus laevis (African clawed frog)
6F
(A1)
60S ribosomal protein L8polymer25727980.71UniProt (A0A1L8H6H2)Xenopus laevis (African clawed frog)
7G
(A2)
40S ribosomal protein SApolymer30634027.21UniProt (Q7ZX07)
Pfam (PF00318)
Pfam (PF16122)
Xenopus laevis (African clawed frog)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
8H
(B1)
Rpl3-prov proteinpolymer40346144.11UniProt (Q7ZYR1)
Pfam (PF00297)
Xenopus laevis (African clawed frog)
9I
(B2)
40S ribosomal protein S3a-Apolymer26429998.01UniProt (Q801S3)
Pfam (PF01015)
Xenopus laevis (African clawed frog)
10J
(C1)
60S ribosomal protein L4-Bpolymer40145525.81UniProt (P02385)
Pfam (PF00573)
Pfam (PF14374)
Xenopus laevis (African clawed frog)L1B
11K
(C2)
40S ribosomal protein S2polymer28130326.21UniProt (Q7T0R9)
Pfam (PF00333)
Pfam (PF03719)
Xenopus laevis (African clawed frog)
12L
(D1)
Rpl5-b proteinpolymer29634066.21UniProt (Q8AVI7)
Pfam (PF17144)
Pfam (PF14204)
Xenopus laevis (African clawed frog)
13M
(D2)
DNA-(apurinic or apyrimidinic site) lyasepolymer24627026.71UniProt (Q7ZYT3)
Pfam (PF07650)
Pfam (PF00189)
Xenopus laevis (African clawed frog)
14N
(E1)
60S ribosomal protein L6polymer25829743.51UniProt (Q6DJF7)
Pfam (PF03868)
Pfam (PF01159)
Xenopus laevis (African clawed frog)
15O
(E2)
40S ribosomal protein S4polymer26329722.91UniProt (P49401)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Xenopus laevis (African clawed frog)
16P
(F1)
MGC130910 proteinpolymer24628762.41UniProt (Q3B8I3)
Pfam (PF08079)
Pfam (PF00327)
Xenopus laevis (African clawed frog)
17Q
(F2)
Ribosomal_S7 domain-containing proteinpolymer20322780.31UniProt (A0A1L8F8E2)
Pfam (PF00177)
Xenopus laevis (African clawed frog)
18R
(G1)
60S ribosomal protein L7apolymer26629939.71UniProt (Q6GQB2)
Pfam (PF01248)
Xenopus laevis (African clawed frog)
19S
(G2)
40S ribosomal protein S6polymer24928778.81UniProt (Q7ZYU0)
Pfam (PF01092)
Xenopus laevis (African clawed frog)
20T
(H1)
60S ribosomal protein L9polymer19221934.61UniProt (A0A1L8HTS7)Xenopus laevis (African clawed frog)
21U
(H2)
40S ribosomal protein S7polymer19422226.01UniProt (P02362)
Pfam (PF01251)
Xenopus laevis (African clawed frog)40S ribosomal protein S8
22V
(I1)
Ribosomal_L16 domain-containing proteinpolymer21524634.11UniProt (A0A1L8F5F1)
Pfam (PF00252)
Xenopus laevis (African clawed frog)
23W
(I2)
40S ribosomal protein S8polymer20824109.31UniProt (Q6DJI0)
Pfam (PF01201)
Xenopus laevis (African clawed frog)
24X
(J1)
60S ribosomal protein L11polymer17720215.51UniProt (Q66KY6)
UniProt (by SIFTS) (A0AA97PZC8)
Xenopus laevis (African clawed frog)
25Y
(J2)
40S ribosomal protein S9polymer19422627.61UniProt (Q7ZYU4)
Pfam (PF00163)
Pfam (PF01479)
Xenopus laevis (African clawed frog)
26Z
(K2)
40S ribosomal protein S10polymer16518918.81UniProt (Q07254)
Pfam (PF03501)
Xenopus laevis (African clawed frog)
27AA
(L1)
60S ribosomal protein L13polymer21124257.71UniProt (Q6DJN5)
Pfam (PF01294)
Xenopus laevis (African clawed frog)
28BA
(L2)
40S ribosomal protein S11polymer15818428.61UniProt (Q7SZ77)
Pfam (PF16205)
Pfam (PF00366)
Xenopus laevis (African clawed frog)
29CA
(M1)
60S ribosomal protein L14polymer13816174.31UniProt (A0A1L8FWH1)
Pfam (PF01929)
Xenopus laevis (African clawed frog)
30DA
(N1)
Ribosomal protein L15polymer20424119.31UniProt (A0A1L8FRG2)
Pfam (PF00827)
Xenopus laevis (African clawed frog)
31EA
(N2)
40S ribosomal protein S13polymer15117287.41UniProt (P49393)
Pfam (PF08069)
Pfam (PF00312)
Xenopus laevis (African clawed frog)
32FA
(O1)
60S ribosomal protein L13apolymer23126450.81UniProt (A0A1L8ENM5)
Pfam (PF00572)
Xenopus laevis (African clawed frog)
33GA
(O2)
Rps14polymer15116302.81Xenopus laevis (African clawed frog)
34HA
(P1)
60S ribosomal protein L17polymer18421457.21UniProt (A0A1L8I3J8)
Pfam (PF00237)
Xenopus laevis (African clawed frog)
35IA
(P2)
40S ribosomal protein S15polymer14517010.21UniProt (P20342)
Pfam (PF00203)
Xenopus laevis (African clawed frog)RIG protein
36JA
(Q1)
Ribosomal_L18e/L15P domain-containing proteinpolymer18821659.81UniProt (A0A1L8FN04)Xenopus laevis (African clawed frog)
37KA
(Q2)
Rps16 proteinpolymer14616361.21UniProt (Q3KQC9)
Pfam (PF00380)
Xenopus laevis (African clawed frog)
38LA
(R1)
60S ribosomal protein L19polymer19723550.31UniProt (Q7ZYS1)
Pfam (PF01280)
Xenopus laevis (African clawed frog)
39MA
(R2)
40S ribosomal protein S17polymer13515552.11UniProt (Q6GNF4)
Pfam (PF00833)
Xenopus laevis (African clawed frog)
40NA
(S1)
60S ribosomal protein L18apolymer17620697.51UniProt (Q7SZB7)
Pfam (PF01775)
Xenopus laevis (African clawed frog)
41OA
(S2)
40S ribosomal protein S18polymer15217717.71UniProt (Q6NTT2)
Pfam (PF00416)
Xenopus laevis (African clawed frog)
42PA
(T1)
60S ribosomal protein L21polymer16018707.01UniProt (Q6GP41)
Pfam (PF01157)
Xenopus laevis (African clawed frog)
43QA
(T2)
40S ribosomal protein S19polymer14616079.61UniProt (A0A310TRG4)
Pfam (PF01090)
Xenopus laevis (African clawed frog)
44RA
(U1)
60S ribosomal protein L22polymer12814843.01UniProt (P50886)
Pfam (PF01776)
Xenopus laevis (African clawed frog)
45SA
(U2)
40S ribosomal protein S20polymer11913381.71UniProt (P23403)
Pfam (PF00338)
Xenopus laevis (African clawed frog)S22
46TA
(V1)
60S ribosomal protein L23polymer14014878.51UniProt (Q6GNH1)
Pfam (PF00238)
Xenopus laevis (African clawed frog)
47UA
(V2)
40S ribosomal protein S21polymer839227.51UniProt (Q6AZJ9)
Pfam (PF01249)
Xenopus laevis (African clawed frog)
48VA
(W1)
TRASH domain-containing proteinpolymer15517722.01UniProt (A0A1L8HGE0)
Pfam (PF01246)
Xenopus laevis (African clawed frog)
49WA
(W2)
40S ribosomal protein S15apolymer13014881.61UniProt (Q4QR44)
Pfam (PF00410)
Xenopus laevis (African clawed frog)
50XA
(X1)
Ribosomal_L23eN domain-containing proteinpolymer15517718.11UniProt (A0A1L8H4S4)
Pfam (PF03939)
Pfam (PF00276)
Xenopus laevis (African clawed frog)
51YA
(X2)
40S ribosomal protein S23polymer14315803.61UniProt (Q6AZL9)
Pfam (PF00164)
Xenopus laevis (African clawed frog)
52ZA
(Y1)
KOW domain-containing proteinpolymer14517235.31UniProt (A0A1L8GXU8)Xenopus laevis (African clawed frog)
53AB
(Y2)
40S ribosomal protein S24polymer13215324.21UniProt (P02377)
Pfam (PF01282)
Xenopus laevis (African clawed frog)S19
54BB
(Z1)
60S ribosomal protein L27polymer13615864.81UniProt (Q6PHL5)
Pfam (PF00467)
Pfam (PF01777)
Xenopus laevis (African clawed frog)
55CB
(Z2)
40S ribosomal protein S25polymer12513863.31UniProt (Q6DJJ1)
Pfam (PF03297)
Xenopus laevis (African clawed frog)
56DB
(a1)
60S ribosomal protein L27apolymer14816636.61UniProt (Q7SZB2)
Pfam (PF00828)
Xenopus laevis (African clawed frog)
57EB
(a2)
40S ribosomal protein S26polymer11513125.61UniProt (Q6AZL7)
Pfam (PF01283)
Xenopus laevis (African clawed frog)
58FB
(b1)
60S ribosomal protein L29polymer758596.11UniProt (Q66KW1)
Pfam (PF01779)
Xenopus laevis (African clawed frog)
59GB
(b2)
40S ribosomal protein S27polymer849480.21UniProt (A0A1L8EJM5)
Pfam (PF01667)
Xenopus laevis (African clawed frog)
60HB
(c1)
60S ribosomal protein L30polymer11612959.31UniProt (Q7SZC0)
Pfam (PF01248)
Xenopus laevis (African clawed frog)
61IB
(c2)
40S ribosomal protein S28polymer697852.11UniProt (Q66KP7)
Pfam (PF01200)
Xenopus laevis (African clawed frog)
62JB
(d1)
60S ribosomal protein L31polymer12514549.01UniProt (Q6NUH0)
Pfam (PF01198)
Xenopus laevis (African clawed frog)
63KB
(d2)
40S ribosomal protein S29polymer8610202.91UniProt (A0A1L8F058)Xenopus laevis (African clawed frog)
64LB
(e1)
Rpl32polymer13515818.81UniProt (A0A1L8GHL2)
Pfam (PF01655)
Xenopus laevis (African clawed frog)
65MB
(e2)
40S ribosomal protein S30polymer13314537.81UniProt (Q4KLF0)
Pfam (PF00240)
Pfam (PF04758)
Xenopus laevis (African clawed frog)
66NB
(f1)
60S ribosomal protein L35apolymer11012630.81UniProt (P02434)
Pfam (PF01247)
Xenopus laevis (African clawed frog)L32
67OB
(g1)
60S ribosomal protein L34polymer11713325.11UniProt (A0A1L8HUR4)
Pfam (PF01199)
Xenopus laevis (African clawed frog)
68PB
(g2)
Gnb2l1-prov proteinpolymer31735107.61UniProt (Q8AVP6)
Pfam (PF00400)
Xenopus laevis (African clawed frog)LOC446289 protein
69QB
(h1)
60S ribosomal protein L35polymer12314492.51UniProt (Q4FZQ7)
Pfam (PF00831)
Xenopus laevis (African clawed frog)
70RB
(i1)
60S ribosomal protein L36polymer10512363.01UniProt (Q66KU4)
Pfam (PF01158)
Xenopus laevis (African clawed frog)
71SB
(i2)
HABP4_PAI-RBP1 domain-containing proteinpolymer37842746.21UniProt (A0A1L8HPG3)Xenopus laevis (African clawed frog)
72TB
(j1)
Ribosomal protein L37polymer9711030.91UniProt (A0A1L8I2F1)
Pfam (PF01907)
Xenopus laevis (African clawed frog)
73UB
(k1)
60S ribosomal protein L38polymer708226.91UniProt (Q66KV2)
Pfam (PF01781)
Xenopus laevis (African clawed frog)
74VB
(l1)
MGC116452 proteinpolymer516398.71UniProt (Q4FZP7)
Pfam (PF00832)
Xenopus laevis (African clawed frog)MGC116477 protein
75WB
(m1)
60S ribosomal protein L40polymer12814758.41UniProt (Q6GQF3)
Pfam (PF00240)
Pfam (PF01020)
Xenopus laevis (African clawed frog)CEP52,Ubiquitin,Ubiquitin-60S ribosomal protein L40
76XB
(n1)
Rpl41polymer253473.51Xenopus laevis (African clawed frog)
77YB
(o1)
MGC85428 proteinpolymer10612496.91UniProt (Q66KU5)
Pfam (PF00935)
Xenopus laevis (African clawed frog)
78ZB
(p1)
Rpl37apolymer9210283.41UniProt (A0A1L8H102)
Pfam (PF01780)
Xenopus laevis (African clawed frog)
79AC
(r1)
60S ribosomal protein L28polymer13715587.41UniProt (Q66KV6)
Pfam (PF01778)
Xenopus laevis (African clawed frog)
80BC
(s1)
Death-associated protein-like 1-Bpolymer11312548.71UniProt (A3KMU5)
Pfam (PF15228)
Xenopus laevis (African clawed frog)
81CC
(v2)
Eef2-prov proteinpolymer85895552.31UniProt (Q7ZXP8)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF14492)
Pfam (PF03764)
Pfam (PF00679)
Xenopus laevis (African clawed frog)
82AD, AE, AF, AG, AH...
(51, A1, B1, C1, V1...)
MAGNESIUM IONnon-polymer24.3134Chemie (MG)
83FH, GH, IH, JH, LH...
(a2, d2, g1, j1, m1...)
ZINC IONnon-polymer65.47Chemie (ZN)
Sequence modifications
22: 1 - 1826 (GenBank: X04025.1)
PDBExternal DatabaseDetails
C 287U 287conflict
D2: 1 - 246 (UniProt: Q7ZYT3)
PDBExternal DatabaseDetails
Gly 83Ser 83conflict
F1: 1 - 246 (UniProt: Q3B8I3)
PDBExternal DatabaseDetails
Ala 134Val 134conflict
L2: 1 - 160 (UniProt: Q7SZ77)
PDBExternal DatabaseDetails
Ala 153Thr 151conflict
Q1: 1 - 188 (UniProt: A0A1L8FN04)
PDBExternal DatabaseDetails
Ala 116Ser 161conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains81
Total formula weight3584266.0
Non-Polymers*Number of molecules141
Total formula weight3714.7
All*Total formula weight3587980.7
*Water molecules are not included.

227111

PDB entries from 2024-11-06

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