Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7OYC

Cryo-EM structure of the Xenopus egg 80S ribosome

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
11	0003723	molecular_function	RNA binding
11	0003743	molecular_function	translation initiation factor activity
11	0003746	molecular_function	translation elongation factor activity
11	0005515	molecular_function	protein binding
11	0005634	cellular_component	nucleus
11	0005737	cellular_component	cytoplasm
11	0005789	cellular_component	endoplasmic reticulum membrane
11	0006412	biological_process	translation
11	0006413	biological_process	translational initiation
11	0006414	biological_process	translational elongation
11	0043022	molecular_function	ribosome binding
11	0045901	biological_process	positive regulation of translational elongation
11	0045905	biological_process	positive regulation of translational termination
A1	0003723	molecular_function	RNA binding
A1	0003735	molecular_function	structural constituent of ribosome
A1	0005840	cellular_component	ribosome
A1	0006412	biological_process	translation
A1	0015934	cellular_component	large ribosomal subunit
A2	0000028	biological_process	ribosomal small subunit assembly
A2	0003735	molecular_function	structural constituent of ribosome
A2	0005055	molecular_function	laminin receptor activity
A2	0005634	cellular_component	nucleus
A2	0005737	cellular_component	cytoplasm
A2	0005840	cellular_component	ribosome
A2	0005886	cellular_component	plasma membrane
A2	0006412	biological_process	translation
A2	0007155	biological_process	cell adhesion
A2	0015935	cellular_component	small ribosomal subunit
A2	0022627	cellular_component	cytosolic small ribosomal subunit
A2	0043236	molecular_function	laminin binding
A2	1990904	cellular_component	ribonucleoprotein complex
B1	0003723	molecular_function	RNA binding
B1	0003735	molecular_function	structural constituent of ribosome
B1	0005730	cellular_component	nucleolus
B1	0005737	cellular_component	cytoplasm
B1	0005840	cellular_component	ribosome
B1	0006412	biological_process	translation
B1	0022625	cellular_component	cytosolic large ribosomal subunit
B1	1990904	cellular_component	ribonucleoprotein complex
B2	0003735	molecular_function	structural constituent of ribosome
B2	0005634	cellular_component	nucleus
B2	0005730	cellular_component	nucleolus
B2	0005737	cellular_component	cytoplasm
B2	0005829	cellular_component	cytosol
B2	0005840	cellular_component	ribosome
B2	0006412	biological_process	translation
B2	0022627	cellular_component	cytosolic small ribosomal subunit
B2	0032040	cellular_component	small-subunit processome
B2	0042274	biological_process	ribosomal small subunit biogenesis
B2	1990904	cellular_component	ribonucleoprotein complex
C1	0003723	molecular_function	RNA binding
C1	0003735	molecular_function	structural constituent of ribosome
C1	0005737	cellular_component	cytoplasm
C1	0005840	cellular_component	ribosome
C1	0006412	biological_process	translation
C1	0022625	cellular_component	cytosolic large ribosomal subunit
C1	1990904	cellular_component	ribonucleoprotein complex
C2	0003723	molecular_function	RNA binding
C2	0003735	molecular_function	structural constituent of ribosome
C2	0005840	cellular_component	ribosome
C2	0006412	biological_process	translation
C2	0015935	cellular_component	small ribosomal subunit
C2	0022627	cellular_component	cytosolic small ribosomal subunit
C2	1990904	cellular_component	ribonucleoprotein complex
D1	0000027	biological_process	ribosomal large subunit assembly
D1	0003723	molecular_function	RNA binding
D1	0003735	molecular_function	structural constituent of ribosome
D1	0005730	cellular_component	nucleolus
D1	0005737	cellular_component	cytoplasm
D1	0005840	cellular_component	ribosome
D1	0006412	biological_process	translation
D1	0008097	molecular_function	5S rRNA binding
D1	0019843	molecular_function	rRNA binding
D1	0022625	cellular_component	cytosolic large ribosomal subunit
D1	1990904	cellular_component	ribonucleoprotein complex
D2	0003723	molecular_function	RNA binding
D2	0003735	molecular_function	structural constituent of ribosome
D2	0005634	cellular_component	nucleus
D2	0005730	cellular_component	nucleolus
D2	0005743	cellular_component	mitochondrial inner membrane
D2	0005819	cellular_component	spindle
D2	0005840	cellular_component	ribosome
D2	0006281	biological_process	DNA repair
D2	0006412	biological_process	translation
D2	0006417	biological_process	regulation of translation
D2	0006915	biological_process	apoptotic process
D2	0006974	biological_process	DNA damage response
D2	0015935	cellular_component	small ribosomal subunit
D2	0016829	molecular_function	lyase activity
D2	0022626	cellular_component	cytosolic ribosome
D2	0022627	cellular_component	cytosolic small ribosomal subunit
D2	0051301	biological_process	cell division
D2	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D2	1990904	cellular_component	ribonucleoprotein complex
D2	2001235	biological_process	positive regulation of apoptotic signaling pathway
E1	0000027	biological_process	ribosomal large subunit assembly
E1	0002181	biological_process	cytoplasmic translation
E1	0003723	molecular_function	RNA binding
E1	0003735	molecular_function	structural constituent of ribosome
E1	0005737	cellular_component	cytoplasm
E1	0005783	cellular_component	endoplasmic reticulum
E1	0005829	cellular_component	cytosol
E1	0005840	cellular_component	ribosome
E1	0006412	biological_process	translation
E1	0015934	cellular_component	large ribosomal subunit
E1	0022625	cellular_component	cytosolic large ribosomal subunit
E1	1990904	cellular_component	ribonucleoprotein complex
E2	0003723	molecular_function	RNA binding
E2	0003735	molecular_function	structural constituent of ribosome
E2	0005737	cellular_component	cytoplasm
E2	0005840	cellular_component	ribosome
E2	0006412	biological_process	translation
E2	0019843	molecular_function	rRNA binding
E2	0022627	cellular_component	cytosolic small ribosomal subunit
E2	1990904	cellular_component	ribonucleoprotein complex
F1	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F1	0003723	molecular_function	RNA binding
F1	0003735	molecular_function	structural constituent of ribosome
F1	0005737	cellular_component	cytoplasm
F1	0005840	cellular_component	ribosome
F1	0022625	cellular_component	cytosolic large ribosomal subunit
F1	1990904	cellular_component	ribonucleoprotein complex
F2	0003723	molecular_function	RNA binding
F2	0003729	molecular_function	mRNA binding
F2	0003735	molecular_function	structural constituent of ribosome
F2	0005840	cellular_component	ribosome
F2	0006412	biological_process	translation
F2	0015935	cellular_component	small ribosomal subunit
F2	0019843	molecular_function	rRNA binding
F2	0022626	cellular_component	cytosolic ribosome
F2	0022627	cellular_component	cytosolic small ribosomal subunit
F2	1990904	cellular_component	ribonucleoprotein complex
G1	0000470	biological_process	maturation of LSU-rRNA
G1	0003723	molecular_function	RNA binding
G1	0005840	cellular_component	ribosome
G1	0022625	cellular_component	cytosolic large ribosomal subunit
G1	0042254	biological_process	ribosome biogenesis
G1	1990904	cellular_component	ribonucleoprotein complex
G2	0003735	molecular_function	structural constituent of ribosome
G2	0005840	cellular_component	ribosome
G2	0006412	biological_process	translation
G2	1990904	cellular_component	ribonucleoprotein complex
H1	0003735	molecular_function	structural constituent of ribosome
H1	0005840	cellular_component	ribosome
H1	0006412	biological_process	translation
H1	0019843	molecular_function	rRNA binding
H2	0003735	molecular_function	structural constituent of ribosome
H2	0005634	cellular_component	nucleus
H2	0005737	cellular_component	cytoplasm
H2	0005813	cellular_component	centrosome
H2	0005840	cellular_component	ribosome
H2	0006364	biological_process	rRNA processing
H2	0006412	biological_process	translation
H2	0022627	cellular_component	cytosolic small ribosomal subunit
H2	0030686	cellular_component	90S preribosome
H2	0032040	cellular_component	small-subunit processome
H2	0042274	biological_process	ribosomal small subunit biogenesis
H2	1990904	cellular_component	ribonucleoprotein complex
I1	0003735	molecular_function	structural constituent of ribosome
I1	0005737	cellular_component	cytoplasm
I1	0005840	cellular_component	ribosome
I1	0006412	biological_process	translation
I1	0022625	cellular_component	cytosolic large ribosomal subunit
I1	1990904	cellular_component	ribonucleoprotein complex
I2	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I2	0003735	molecular_function	structural constituent of ribosome
I2	0005737	cellular_component	cytoplasm
I2	0005840	cellular_component	ribosome
I2	0006412	biological_process	translation
I2	0022627	cellular_component	cytosolic small ribosomal subunit
I2	1990904	cellular_component	ribonucleoprotein complex
J1	0003735	molecular_function	structural constituent of ribosome
J1	0005840	cellular_component	ribosome
J1	0006412	biological_process	translation
J1	0019843	molecular_function	rRNA binding
J1	1990904	cellular_component	ribonucleoprotein complex
J2	0003723	molecular_function	RNA binding
J2	0003735	molecular_function	structural constituent of ribosome
J2	0005840	cellular_component	ribosome
J2	0006412	biological_process	translation
J2	0015935	cellular_component	small ribosomal subunit
J2	0019843	molecular_function	rRNA binding
J2	0022627	cellular_component	cytosolic small ribosomal subunit
J2	0042274	biological_process	ribosomal small subunit biogenesis
J2	0043226	cellular_component	organelle
J2	1990904	cellular_component	ribonucleoprotein complex
K2	0003723	molecular_function	RNA binding
K2	0003735	molecular_function	structural constituent of ribosome
K2	0005730	cellular_component	nucleolus
K2	0005737	cellular_component	cytoplasm
K2	0005840	cellular_component	ribosome
K2	0022626	cellular_component	cytosolic ribosome
K2	0022627	cellular_component	cytosolic small ribosomal subunit
K2	1990904	cellular_component	ribonucleoprotein complex
L1	0003723	molecular_function	RNA binding
L1	0003735	molecular_function	structural constituent of ribosome
L1	0005840	cellular_component	ribosome
L1	0006412	biological_process	translation
L1	0022625	cellular_component	cytosolic large ribosomal subunit
L1	1990904	cellular_component	ribonucleoprotein complex
L2	0003735	molecular_function	structural constituent of ribosome
L2	0005840	cellular_component	ribosome
L2	0006412	biological_process	translation
L2	0019843	molecular_function	rRNA binding
L2	0022627	cellular_component	cytosolic small ribosomal subunit
L2	1990904	cellular_component	ribonucleoprotein complex
M1	0003723	molecular_function	RNA binding
M1	0003735	molecular_function	structural constituent of ribosome
M1	0005737	cellular_component	cytoplasm
M1	0005840	cellular_component	ribosome
M1	0006412	biological_process	translation
M1	0015934	cellular_component	large ribosomal subunit
M1	0022625	cellular_component	cytosolic large ribosomal subunit
M1	0042273	biological_process	ribosomal large subunit biogenesis
M1	1990904	cellular_component	ribonucleoprotein complex
N1	0002181	biological_process	cytoplasmic translation
N1	0003723	molecular_function	RNA binding
N1	0003735	molecular_function	structural constituent of ribosome
N1	0005840	cellular_component	ribosome
N1	0006412	biological_process	translation
N1	0022625	cellular_component	cytosolic large ribosomal subunit
N1	0044391	cellular_component	ribosomal subunit
N1	1990904	cellular_component	ribonucleoprotein complex
N2	0003735	molecular_function	structural constituent of ribosome
N2	0005730	cellular_component	nucleolus
N2	0005737	cellular_component	cytoplasm
N2	0005840	cellular_component	ribosome
N2	0006412	biological_process	translation
N2	0022627	cellular_component	cytosolic small ribosomal subunit
N2	0070181	molecular_function	small ribosomal subunit rRNA binding
N2	1990904	cellular_component	ribonucleoprotein complex
O1	0003729	molecular_function	mRNA binding
O1	0003735	molecular_function	structural constituent of ribosome
O1	0005840	cellular_component	ribosome
O1	0006412	biological_process	translation
O1	0015934	cellular_component	large ribosomal subunit
O1	0017148	biological_process	negative regulation of translation
O1	0022625	cellular_component	cytosolic large ribosomal subunit
O1	1990904	cellular_component	ribonucleoprotein complex
O2	0003735	molecular_function	structural constituent of ribosome
O2	0005840	cellular_component	ribosome
O2	0006412	biological_process	translation
P1	0002181	biological_process	cytoplasmic translation
P1	0003735	molecular_function	structural constituent of ribosome
P1	0005840	cellular_component	ribosome
P1	0006412	biological_process	translation
P1	0015934	cellular_component	large ribosomal subunit
P1	0022625	cellular_component	cytosolic large ribosomal subunit
P1	0022626	cellular_component	cytosolic ribosome
P1	1990904	cellular_component	ribonucleoprotein complex
P2	0000028	biological_process	ribosomal small subunit assembly
P2	0003723	molecular_function	RNA binding
P2	0003735	molecular_function	structural constituent of ribosome
P2	0005737	cellular_component	cytoplasm
P2	0005840	cellular_component	ribosome
P2	0006412	biological_process	translation
P2	0015935	cellular_component	small ribosomal subunit
P2	0022627	cellular_component	cytosolic small ribosomal subunit
P2	1990904	cellular_component	ribonucleoprotein complex
Q1	0003735	molecular_function	structural constituent of ribosome
Q1	0005840	cellular_component	ribosome
Q1	0006412	biological_process	translation
Q2	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q2	0003723	molecular_function	RNA binding
Q2	0003735	molecular_function	structural constituent of ribosome
Q2	0005840	cellular_component	ribosome
Q2	0006412	biological_process	translation
Q2	0015935	cellular_component	small ribosomal subunit
Q2	0022626	cellular_component	cytosolic ribosome
Q2	0022627	cellular_component	cytosolic small ribosomal subunit
Q2	1990904	cellular_component	ribonucleoprotein complex
R1	0003723	molecular_function	RNA binding
R1	0003735	molecular_function	structural constituent of ribosome
R1	0005737	cellular_component	cytoplasm
R1	0005840	cellular_component	ribosome
R1	0006412	biological_process	translation
R1	0022625	cellular_component	cytosolic large ribosomal subunit
R1	1990904	cellular_component	ribonucleoprotein complex
R2	0003735	molecular_function	structural constituent of ribosome
R2	0005840	cellular_component	ribosome
R2	0006412	biological_process	translation
R2	0022626	cellular_component	cytosolic ribosome
R2	0022627	cellular_component	cytosolic small ribosomal subunit
R2	1990904	cellular_component	ribonucleoprotein complex
S1	0002181	biological_process	cytoplasmic translation
S1	0003735	molecular_function	structural constituent of ribosome
S1	0005840	cellular_component	ribosome
S1	0006412	biological_process	translation
S1	0022625	cellular_component	cytosolic large ribosomal subunit
S1	1990904	cellular_component	ribonucleoprotein complex
S2	0003676	molecular_function	nucleic acid binding
S2	0003723	molecular_function	RNA binding
S2	0003735	molecular_function	structural constituent of ribosome
S2	0005737	cellular_component	cytoplasm
S2	0005829	cellular_component	cytosol
S2	0005840	cellular_component	ribosome
S2	0006412	biological_process	translation
S2	0015935	cellular_component	small ribosomal subunit
S2	0019843	molecular_function	rRNA binding
S2	1990904	cellular_component	ribonucleoprotein complex
T1	0003735	molecular_function	structural constituent of ribosome
T1	0005840	cellular_component	ribosome
T1	0006412	biological_process	translation
T1	0022625	cellular_component	cytosolic large ribosomal subunit
T1	1990904	cellular_component	ribonucleoprotein complex
T2	0003735	molecular_function	structural constituent of ribosome
T2	0005840	cellular_component	ribosome
T2	0006412	biological_process	translation
U1	0002181	biological_process	cytoplasmic translation
U1	0003723	molecular_function	RNA binding
U1	0003735	molecular_function	structural constituent of ribosome
U1	0005737	cellular_component	cytoplasm
U1	0005840	cellular_component	ribosome
U1	0006412	biological_process	translation
U1	1990904	cellular_component	ribonucleoprotein complex
U2	0003723	molecular_function	RNA binding
U2	0003735	molecular_function	structural constituent of ribosome
U2	0005737	cellular_component	cytoplasm
U2	0005829	cellular_component	cytosol
U2	0005840	cellular_component	ribosome
U2	0006412	biological_process	translation
U2	0015935	cellular_component	small ribosomal subunit
U2	0022627	cellular_component	cytosolic small ribosomal subunit
U2	1990904	cellular_component	ribonucleoprotein complex
V1	0003735	molecular_function	structural constituent of ribosome
V1	0005840	cellular_component	ribosome
V1	0006412	biological_process	translation
V1	0015934	cellular_component	large ribosomal subunit
V1	0022625	cellular_component	cytosolic large ribosomal subunit
V1	0070180	molecular_function	large ribosomal subunit rRNA binding
V1	1990904	cellular_component	ribonucleoprotein complex
V2	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V2	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V2	0002181	biological_process	cytoplasmic translation
V2	0003735	molecular_function	structural constituent of ribosome
V2	0005737	cellular_component	cytoplasm
V2	0005791	cellular_component	rough endoplasmic reticulum
V2	0005829	cellular_component	cytosol
V2	0005840	cellular_component	ribosome
V2	0006412	biological_process	translation
V2	0022626	cellular_component	cytosolic ribosome
V2	0022627	cellular_component	cytosolic small ribosomal subunit
V2	1990904	cellular_component	ribonucleoprotein complex
W1	0002181	biological_process	cytoplasmic translation
W1	0003729	molecular_function	mRNA binding
W1	0003735	molecular_function	structural constituent of ribosome
W1	0005737	cellular_component	cytoplasm
W1	0005840	cellular_component	ribosome
W1	0022625	cellular_component	cytosolic large ribosomal subunit
W1	1990904	cellular_component	ribonucleoprotein complex
W2	0003735	molecular_function	structural constituent of ribosome
W2	0005840	cellular_component	ribosome
W2	0006412	biological_process	translation
W2	1990904	cellular_component	ribonucleoprotein complex
X1	0003723	molecular_function	RNA binding
X1	0003735	molecular_function	structural constituent of ribosome
X1	0005634	cellular_component	nucleus
X1	0005737	cellular_component	cytoplasm
X1	0005840	cellular_component	ribosome
X1	0006412	biological_process	translation
X1	0019843	molecular_function	rRNA binding
X1	0022625	cellular_component	cytosolic large ribosomal subunit
X1	1990904	cellular_component	ribonucleoprotein complex
X2	0003735	molecular_function	structural constituent of ribosome
X2	0005791	cellular_component	rough endoplasmic reticulum
X2	0005840	cellular_component	ribosome
X2	0006412	biological_process	translation
X2	0015935	cellular_component	small ribosomal subunit
X2	0022626	cellular_component	cytosolic ribosome
X2	0022627	cellular_component	cytosolic small ribosomal subunit
X2	1990904	cellular_component	ribonucleoprotein complex
Y1	0003723	molecular_function	RNA binding
Y1	0003735	molecular_function	structural constituent of ribosome
Y1	0005840	cellular_component	ribosome
Y1	0006412	biological_process	translation
Y1	0015934	cellular_component	large ribosomal subunit
Y2	0003735	molecular_function	structural constituent of ribosome
Y2	0005730	cellular_component	nucleolus
Y2	0005737	cellular_component	cytoplasm
Y2	0005840	cellular_component	ribosome
Y2	0006412	biological_process	translation
Y2	0022627	cellular_component	cytosolic small ribosomal subunit
Y2	0032040	cellular_component	small-subunit processome
Y2	0042274	biological_process	ribosomal small subunit biogenesis
Y2	1990904	cellular_component	ribonucleoprotein complex
Z1	0003735	molecular_function	structural constituent of ribosome
Z1	0005791	cellular_component	rough endoplasmic reticulum
Z1	0005840	cellular_component	ribosome
Z1	0006412	biological_process	translation
Z1	0022625	cellular_component	cytosolic large ribosomal subunit
Z1	1990904	cellular_component	ribonucleoprotein complex
Z2	0003735	molecular_function	structural constituent of ribosome
Z2	0005840	cellular_component	ribosome
Z2	0022626	cellular_component	cytosolic ribosome
Z2	1990904	cellular_component	ribonucleoprotein complex
a1	0003735	molecular_function	structural constituent of ribosome
a1	0005840	cellular_component	ribosome
a1	0006412	biological_process	translation
a1	0015934	cellular_component	large ribosomal subunit
a1	0022625	cellular_component	cytosolic large ribosomal subunit
a1	1990904	cellular_component	ribonucleoprotein complex
a2	0003729	molecular_function	mRNA binding
a2	0003735	molecular_function	structural constituent of ribosome
a2	0005840	cellular_component	ribosome
a2	0006412	biological_process	translation
a2	0022626	cellular_component	cytosolic ribosome
a2	0022627	cellular_component	cytosolic small ribosomal subunit
a2	1990904	cellular_component	ribonucleoprotein complex
b1	0002181	biological_process	cytoplasmic translation
b1	0003735	molecular_function	structural constituent of ribosome
b1	0005840	cellular_component	ribosome
b1	0006412	biological_process	translation
b1	0022625	cellular_component	cytosolic large ribosomal subunit
b1	1990904	cellular_component	ribonucleoprotein complex
b2	0003735	molecular_function	structural constituent of ribosome
b2	0005840	cellular_component	ribosome
b2	0006412	biological_process	translation
b2	0008270	molecular_function	zinc ion binding
b2	0046872	molecular_function	metal ion binding
b2	1990904	cellular_component	ribonucleoprotein complex
c1	0003723	molecular_function	RNA binding
c1	0003735	molecular_function	structural constituent of ribosome
c1	0005840	cellular_component	ribosome
c1	0022625	cellular_component	cytosolic large ribosomal subunit
c1	1990904	cellular_component	ribonucleoprotein complex
c2	0000028	biological_process	ribosomal small subunit assembly
c2	0003735	molecular_function	structural constituent of ribosome
c2	0005840	cellular_component	ribosome
c2	0006412	biological_process	translation
c2	0022626	cellular_component	cytosolic ribosome
c2	0022627	cellular_component	cytosolic small ribosomal subunit
c2	0030490	biological_process	maturation of SSU-rRNA
c2	1990904	cellular_component	ribonucleoprotein complex
d1	0002181	biological_process	cytoplasmic translation
d1	0003735	molecular_function	structural constituent of ribosome
d1	0005737	cellular_component	cytoplasm
d1	0005840	cellular_component	ribosome
d1	0006412	biological_process	translation
d1	0015934	cellular_component	large ribosomal subunit
d1	0022625	cellular_component	cytosolic large ribosomal subunit
d1	1990904	cellular_component	ribonucleoprotein complex
d2	0003723	molecular_function	RNA binding
d2	0003735	molecular_function	structural constituent of ribosome
d2	0005840	cellular_component	ribosome
d2	0006412	biological_process	translation
d2	0008270	molecular_function	zinc ion binding
d2	0015935	cellular_component	small ribosomal subunit
e1	0003735	molecular_function	structural constituent of ribosome
e1	0005840	cellular_component	ribosome
e1	0006412	biological_process	translation
e1	0022625	cellular_component	cytosolic large ribosomal subunit
e1	1990904	cellular_component	ribonucleoprotein complex
e2	0003735	molecular_function	structural constituent of ribosome
e2	0005840	cellular_component	ribosome
e2	0006412	biological_process	translation
e2	0022627	cellular_component	cytosolic small ribosomal subunit
e2	1990904	cellular_component	ribonucleoprotein complex
f1	0000049	molecular_function	tRNA binding
f1	0002181	biological_process	cytoplasmic translation
f1	0003723	molecular_function	RNA binding
f1	0003735	molecular_function	structural constituent of ribosome
f1	0005737	cellular_component	cytoplasm
f1	0005840	cellular_component	ribosome
f1	0006412	biological_process	translation
f1	0022625	cellular_component	cytosolic large ribosomal subunit
f1	0042273	biological_process	ribosomal large subunit biogenesis
f1	1990904	cellular_component	ribonucleoprotein complex
g1	0003735	molecular_function	structural constituent of ribosome
g1	0005840	cellular_component	ribosome
g1	0006412	biological_process	translation
g2	0005080	molecular_function	protein kinase C binding
g2	0005634	cellular_component	nucleus
g2	0005829	cellular_component	cytosol
g2	0005840	cellular_component	ribosome
g2	0016301	molecular_function	kinase activity
g2	0043022	molecular_function	ribosome binding
g2	0045182	molecular_function	translation regulator activity
g2	0072344	biological_process	rescue of stalled ribosome
g2	1990904	cellular_component	ribonucleoprotein complex
g2	2001125	biological_process	negative regulation of translational frameshifting
h1	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
h1	0003729	molecular_function	mRNA binding
h1	0003735	molecular_function	structural constituent of ribosome
h1	0005840	cellular_component	ribosome
h1	0006412	biological_process	translation
h1	0022625	cellular_component	cytosolic large ribosomal subunit
h1	1990904	cellular_component	ribonucleoprotein complex
i1	0002181	biological_process	cytoplasmic translation
i1	0003735	molecular_function	structural constituent of ribosome
i1	0005737	cellular_component	cytoplasm
i1	0005829	cellular_component	cytosol
i1	0005840	cellular_component	ribosome
i1	0006412	biological_process	translation
i1	0022625	cellular_component	cytosolic large ribosomal subunit
i1	1990904	cellular_component	ribonucleoprotein complex
i2	0003723	molecular_function	RNA binding
j1	0003723	molecular_function	RNA binding
j1	0003735	molecular_function	structural constituent of ribosome
j1	0005840	cellular_component	ribosome
j1	0006412	biological_process	translation
j1	0008270	molecular_function	zinc ion binding
j1	0019843	molecular_function	rRNA binding
j1	0022625	cellular_component	cytosolic large ribosomal subunit
j1	0046872	molecular_function	metal ion binding
j1	1990904	cellular_component	ribonucleoprotein complex
k1	0003735	molecular_function	structural constituent of ribosome
k1	0005840	cellular_component	ribosome
k1	0006412	biological_process	translation
k1	0022618	biological_process	protein-RNA complex assembly
k1	0022625	cellular_component	cytosolic large ribosomal subunit
k1	1990904	cellular_component	ribonucleoprotein complex
l1	0003735	molecular_function	structural constituent of ribosome
l1	0005840	cellular_component	ribosome
l1	0006412	biological_process	translation
l1	0022625	cellular_component	cytosolic large ribosomal subunit
l1	1990904	cellular_component	ribonucleoprotein complex
m1	0003735	molecular_function	structural constituent of ribosome
m1	0005634	cellular_component	nucleus
m1	0005737	cellular_component	cytoplasm
m1	0005840	cellular_component	ribosome
m1	0006412	biological_process	translation
m1	0015934	cellular_component	large ribosomal subunit
m1	0016567	biological_process	protein ubiquitination
m1	0019941	biological_process	modification-dependent protein catabolic process
m1	0031386	molecular_function	protein tag activity
m1	0031625	molecular_function	ubiquitin protein ligase binding
m1	1990904	cellular_component	ribonucleoprotein complex
n1	0003735	molecular_function	structural constituent of ribosome
n1	0005840	cellular_component	ribosome
n1	0006412	biological_process	translation
o1	0003735	molecular_function	structural constituent of ribosome
o1	0005840	cellular_component	ribosome
o1	0006412	biological_process	translation
o1	1990904	cellular_component	ribonucleoprotein complex
p1	0003735	molecular_function	structural constituent of ribosome
p1	0005840	cellular_component	ribosome
p1	0006412	biological_process	translation
p1	0008270	molecular_function	zinc ion binding
p1	0022625	cellular_component	cytosolic large ribosomal subunit
p1	0046872	molecular_function	metal ion binding
p1	0070180	molecular_function	large ribosomal subunit rRNA binding
p1	1990904	cellular_component	ribonucleoprotein complex
r1	0003735	molecular_function	structural constituent of ribosome
r1	0005840	cellular_component	ribosome
r1	0006412	biological_process	translation
r1	0022625	cellular_component	cytosolic large ribosomal subunit
r1	1990904	cellular_component	ribonucleoprotein complex
s1	0006417	biological_process	regulation of translation
s1	0010507	biological_process	negative regulation of autophagy
s1	0030371	molecular_function	translation repressor activity
s1	0031369	molecular_function	translation initiation factor binding
s1	0034198	biological_process	cellular response to amino acid starvation
s1	0043022	molecular_function	ribosome binding
s1	0070513	molecular_function	death domain binding
s1	0097190	biological_process	apoptotic signaling pathway
s1	0141014	biological_process	ribosome hibernation
v2	0000166	molecular_function	nucleotide binding
v2	0003746	molecular_function	translation elongation factor activity
v2	0003924	molecular_function	GTPase activity
v2	0005515	molecular_function	protein binding
v2	0005525	molecular_function	GTP binding
v2	0005634	cellular_component	nucleus
v2	0005737	cellular_component	cytoplasm
v2	0005829	cellular_component	cytosol
v2	0006412	biological_process	translation
v2	0006414	biological_process	translational elongation
v2	0016787	molecular_function	hydrolase activity
v2	0043022	molecular_function	ribosome binding
v2	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
V1	ALA79-ILE105

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
X1	LYS133-VAL148

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
l1	LYS30-ARG46

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
F2	GLU69-ALA95

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyiVLTTSaGIMdheeAR

Chain	Residue	Details
W2	GLY100-ARG117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD

Chain	Residue	Details
O2	LEU116-ASP138

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
X2	LYS60-ARG67

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDtVtVgEcRPLS

Chain	Residue	Details
L2	GLY125-SER137

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. LVYPSEIVGRRirvkldG

Chain	Residue	Details
H2	LEU133-GLY150

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
m1	LYS27-ASP52

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DTrkdEQeRCITIksT

Chain	Residue	Details
v2	ASP58-THR73

site_id	PS00302
Number of Residues	8
Details	IF5A_HYPUSINE Eukaryotic initiation factor 5A hypusine signature. TGKHGhAK

Chain	Residue	Details
11	THR49-LYS56

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKafnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
P2	ASN98-THR122

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
J1	LEU39-THR55

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQvyAirqAiSKSL

Chain	Residue	Details
Q2	GLY74-LEU92

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
U2	ALA43-THR58

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
N2	VAL98-TYR128

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
P1	ARG126-LEU150

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
A1	PRO197-GLU208

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
B1	PHE211-ARG234

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrkAeekIksvG

Chain	Residue	Details
a1	LYS110-GLY141

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
R1	GLN7-PRO26

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
d2	ARG22-ARG44

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK

Chain	Residue	Details
E2	HIS8-LYS22

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE

Chain	Residue	Details
Y2	PHE64-GLU86

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
D2	ALA147-GLY183

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
G2	ILE52-MET63

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
h1	LYS43-VAL57

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIsrn..WRKprG

Chain	Residue	Details
e1	PHE20-GLY40

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI

Chain	Residue	Details
C2	GLY105-ILE137

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRkVLQaLE

Chain	Residue	Details
T2	PRO90-GLU109

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI

Chain	Residue	Details
J2	LEU106-ILE130

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLrlAepYI

Chain	Residue	Details
F1	VAL106-ILE138

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
S2	ARG121-GLN134

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
g2	ALA78-LEU92
g2	ILE120-THR134
g2	ILE165-LEU179
g2	CYS207-LEU221

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GETSGKNV

Chain	Residue	Details
C1	GLY19-VAL26

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
H1	GLN163-LYS184

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
c1	SER24-LEU48

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
R2	ILE41-HIS56

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH

Chain	Residue	Details
a2	TYR73-HIS80

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaalerLkVFdG

Chain	Residue	Details
O1	VAL112-GLY135

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAVcSALaASAlpalimsKGH

Chain	Residue	Details
C1	ASN120-HIS146

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH

Chain	Residue	Details
H2	ARG78-HIS91

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
c2	GLU60-LEU68

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG

Chain	Residue	Details
A2	VAL15-GLY26

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNIP

Chain	Residue	Details
A2	PRO119-PRO143

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
c1	GLU80-GLY100

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
V2	LEU11-ALA19

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD

Chain	Residue	Details
W1	PHE8-ASP25

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HslCrRCG

Chain	Residue	Details
j1	GLY4-GLY23

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciVkGKarLG

Chain	Residue	Details
G1	CYS174-GLY191

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELkaaG

Chain	Residue	Details
L1	ARG71-GLY85

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
f1	GLY72-PRO93

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSMsRL

Chain	Residue	Details
Q1	LYS49-LEU66

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
Z1	GLY125-PHE136

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
Y1	ASP52-VAL70

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
d1	VAL60-GLY74

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TtSnKtrlsRTPGN

Chain	Residue	Details
g1	THR15-ASN28

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG

Chain	Residue	Details
b2	LYS36-GLY68

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NriPLRRahqkFVIATSt.K

Chain	Residue	Details
E1	ASN160-LYS178

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtiqk.GmpHkcYhGkTG

Chain	Residue	Details
T1	GLY37-GLY62

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
o1	LYS61-CYS72

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
i1	PRO52-LYS62

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL

Chain	Residue	Details
B2	LEU62-LEU74

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG

Chain	Residue	Details
I2	ARG11-GLY30

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
N1	ASP46-GLY69

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV

Chain	Residue	Details
I1	ALA108-VAL129

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Hypusine","evidences":[{"source":"UniProtKB","id":"P10160","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	62
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	1
Details	Modified residue: {"description":"Diphthamide","evidences":[{"source":"UniProtKB","id":"P05197","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)