7OWZ
Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine and in the presence of Anderson-Evans type (TEW) and Strandberg type polyoxometalate (POM)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Queuine tRNA-ribosyltransferase accessory subunit 2 | polymer | 419 | 46710.5 | 1 | UniProt (B8ZXI1) Pfam (PF01702) | Mus musculus (Mouse) | Queuine tRNA-ribosyltransferase domain-containing protein 1 |
| 2 | B (C) | Queuine tRNA-ribosyltransferase catalytic subunit 1 | polymer | 395 | 43429.0 | 1 | UniProt (Q9JMA2) Pfam (PF01702) | Mus musculus (Mouse) | Guanine insertion enzyme,tRNA-guanine transglycosylase |
| 3 | C, D (A) | 6-tungstotellurate(VI) | non-polymer | 1614.6 | 2 | Chemie (TEW) | |||
| 4 | E, F (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G (C) | 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one | non-polymer | 277.3 | 1 | Chemie (QEI) | |||
| 6 | H (C) | pentadecaoxodiphosphopentatungstate | non-polymer | 1359.2 | 1 | Chemie (2I2) | |||
| 7 | I, J (A, C) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 2 - 415 (UniProt: B8ZXI1)
C: 11 - 403 (UniProt: Q9JMA2)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | cloning artifact |
| Pro 1 | - | cloning artifact |
| Asp 416 | - | expression tag |
| Asn 417 | - | expression tag |
| Asn 418 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 9 | - | cloning artifact |
| Pro 10 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90139.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 4996.6 | |
| All* | Total formula weight | 95136.0 |
