7OWB

Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-hydroxylase CalMB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein	polymer	370	40304.7	1	UniProt (Q06528) UniProt (A0A2V2Q0Q4) Pfam (PF00891) In PDB	Streptomyces peucetius	COMT,Anthracycline 4-O-methyltransferase
2	A	methyl (1R,2R,4S)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate	non-polymer		569.6	1	Chemie (3VL)
3	A	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)
4		water	water		18.0	32	Chemie (HOH)

Sequence modifications

A: 2 - 285 (UniProt: Q06528)

PDB	External Database	Details
Met -9	-	initiating methionine
Ala -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Arg 0	-	expression tag
Ser 1	-	expression tag

A: 286 - 303 (UniProt: A0A2V2Q0Q4)
A: 304 - 360 (UniProt: Q06528)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	40304.7
Non-Polymers*	Number of molecules	2
	Total formula weight	954.0
All*	Total formula weight	41258.7

*Water molecules are not included.