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7OS2

Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
U5 small nuclear ribonucleoprotein 200 kDa helicasepolymer1739198785.81UniProt (O75643)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF02889)
Homo sapiens (Human)
2B
(C)
Telomere length and silencing protein 1 homologpolymer29334081.51UniProt (Q9NZ63)
Pfam (PF07052)
Homo sapiens (Human)
3C
(J)
Pre-mRNA-processing-splicing factor 8polymer27831861.01UniProt (Q6P2Q9)
Pfam (PF01398)
Pfam (PF08084)
Homo sapiens (Human)
Sequence modifications
B: 394 - 2129 (UniProt: O75643)
PDBExternal DatabaseDetails
Gly 391-expression tag
Ala 392-expression tag
Glu 393-expression tag
Phe 394Met 394expression tag
C: 1 - 289 (UniProt: Q9NZ63)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ala -2-expression tag
Met -1-expression tag
Ala 0-expression tag
J: 2064 - 2335 (UniProt: Q6P2Q9)
PDBExternal DatabaseDetails
Gly 2058-expression tag
Pro 2059-expression tag
Leu 2060-expression tag
Gly 2061-expression tag
Ser 2062-expression tag
Met 2063-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight264728.3
All*Total formula weight264728.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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