7OO3

Pol II-CSB-CSA-DDB1-UVSSA (Structure1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA-directed RNA polymerase II subunit RPB1	polymer	1970	217450.1	1	UniProt (P11414) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) In PDB	Sus scrofa
2	B	DNA-directed RNA polymerase subunit beta	polymer	1174	134041.4	1	UniProt (I3LGP4) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) In PDB	Sus scrofa (Pig)
3	C	DNA-directed RNA polymerase II subunit RPB3	polymer	275	31439.1	1	UniProt (I3LCH3) Pfam (PF01193) Pfam (PF01000) In PDB	Sus scrofa (Pig)
4	D	RPOL4c domain-containing protein	polymer	142	16331.3	1	UniProt (A0A287ADR4) Pfam (PF03874) In PDB	Sus scrofa (Pig)
5	E	DNA-directed RNA polymerase II subunit E	polymer	210	24644.3	1	UniProt (I3LSI7) Pfam (PF03871) Pfam (PF01191) In PDB	Sus scrofa (Pig)	RPB5 homolog
6	F	DNA-directed RNA polymerase II subunit F	polymer	127	14477.0	1	UniProt (F1SKN8) Pfam (PF01192) UniProt (by SIFTS) (A0A4X1VEK9) In PDB	Sus scrofa (Pig)	DNA-directed RNA polymerases I,II,and III subunit RPABC2,RPB6 homolog
7	G	DNA-directed RNA polymerase II subunit RPB7	polymer	172	19314.3	1	UniProt (I3LJZ9) In PDB	Sus scrofa (Pig)
8	H	DNA-directed RNA polymerases I, II, and III subunit RPABC3	polymer	150	17162.3	1	UniProt (A0A4X1ULF2) Pfam (PF03870) UniProt (by SIFTS) (I3LCB2) In PDB	Sus scrofa (Pig)
9	I	DNA-directed RNA polymerase II subunit RPB9	polymer	125	14541.2	1	UniProt (P60899) Pfam (PF02150) Pfam (PF01096) In PDB	Sus scrofa (Pig)	RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5
10	J	DNA-directed RNA polymerases I, II, and III subunit RPABC5	polymer	67	7655.1	1	UniProt (A0A4X1VYD0) Pfam (PF01194) In PDB	Sus scrofa (Pig)
11	K	RNA_pol_L_2 domain-containing protein	polymer	117	13310.3	1	UniProt (A0A4X1UK25) Pfam (PF13656) UniProt (by SIFTS) (F1RKE4) In PDB	Sus scrofa (Pig)
12	L	RNA polymerase II subunit K	polymer	58	7018.2	1	UniProt (I3LN51) Pfam (PF03604) UniProt (by SIFTS) (A0A4X1TRS6) In PDB	Sus scrofa (Pig)
13	N	NTS	polymer	47	14494.3	1		Homo sapiens
14	T	TS	polymer	47	14269.1	1		Homo sapiens
15	P	RNA	polymer	10	3264.0	1		Homo sapiens
16	a	DNA excision repair protein ERCC-8	polymer	396	44107.2	1	UniProt (Q13216) Pfam (PF00400) In PDB	Homo sapiens (Human)	Cockayne syndrome WD repeat protein CSA
17	b	DNA excision repair protein ERCC-6	polymer	1493	168673.5	1	UniProt (Q03468) Pfam (PF00176) Pfam (PF00271) In PDB	Homo sapiens (Human)	ATP-dependent helicase ERCC6,Cockayne syndrome protein CSB
18	x	CSB element	polymer	35	2996.7	1		Homo sapiens (Human)
19	c	UV-stimulated scaffold protein A	polymer	709	80721.7	1	UniProt (Q2YD98) Pfam (PF20867) Pfam (PF09740) In PDB	Homo sapiens (Human)
20	d	DNA damage-binding protein 1	polymer	1143	127369.7	1	UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) In PDB	Homo sapiens (Human)	DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe
21	I, J, L, A, B...	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
22	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Sequence modifications

d: 1 - 1140 (UniProt: Q16531)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	973280.8
Non-Polymers*	Number of molecules	9
	Total formula weight	547.6
All*	Total formula weight	973828.4

*Water molecules are not included.