7OK3
Crystal Structure of KRasG13C in Complex with Nucleotide-based Covalent Inhibitor edaGDP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Isoform 2B of GTPase KRas | polymer | 170 | 19433.9 | 1 | UniProt (P01116-2) Pfam (PF00071) UniProt (by SIFTS) (P01116) In PDB | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
2 | A | edaGDP | non-polymer | 585.4 | 1 | Chemie (VJ8) | |||
3 | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
A: 1 - 169 (UniProt: P01116-2)
PDB | External Database | Details |
---|---|---|
His 0 | - | expression tag |
Cys 13 | Gly 13 | engineered mutation |
Ser 51 | Cys 51 | engineered mutation |
Leu 80 | Cys 80 | engineered mutation |
Ser 118 | Cys 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19433.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 585.4 | |
All* | Total formula weight | 20019.2 |