7OJH
ABCG2 topotecan turnover-1 state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Broad substrate specificity ATP-binding cassette transporter ABCG2 | polymer | 665 | 73526.9 | 2 | UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) In PDB | Homo sapiens (Human) | ATP-binding cassette sub-family G member 2,Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter |
2 | B, A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
3 | B, A | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) | |||
4 | A | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE | non-polymer | 421.4 | 1 | Chemie (TTC) |
Sequence modifications
B, A: 2 - 655 (UniProt: Q9UNQ0)
PDB | External Database | Details |
---|---|---|
Met -9 | - | initiating methionine |
Asp -8 | - | expression tag |
Tyr -7 | - | expression tag |
Lys -6 | - | expression tag |
Asp -5 | - | expression tag |
Asp -4 | - | expression tag |
Asp -3 | - | expression tag |
Asp -2 | - | expression tag |
Lys -1 | - | expression tag |
Gly 0 | - | expression tag |
Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 147053.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 2209.1 | |
All* | Total formula weight | 149263.0 |