7OFE
Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kelch-like ECH-associated protein 1 | polymer | 291 | 31887.6 | 1 | UniProt (Q9Z2X8) Pfam (PF01344) | Mus musculus (Mouse) | Cytosolic inhibitor of Nrf2,INrf2 |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D, E, F, G, H... (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 7 | Chemie (DMS) | |||
| 4 | K (A) | 2-[(9-oxidanylidenefluoren-4-yl)carbonylamino]ethanoic acid | non-polymer | 281.3 | 1 | Chemie (VBQ) | |||
| 5 | L (A) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31887.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1020.3 | |
| All* | Total formula weight | 32908.0 |
