7OCD

Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	Isoform Flip of Glutamate receptor 1	polymer	915	102661.9	2	UniProt (P19490) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1,GluA1
2	C, F (D, B)	Glutamate receptor 2	polymer	860	96247.1	2	UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)
3	D, E (I, J)	Voltage-dependent calcium channel gamma-8 subunit	polymer	423	43576.0	2	UniProt (Q8VHW5) Pfam (PF00822)	Rattus norvegicus (Norway rat)	Neuronal voltage-gated calcium channel gamma-8 subunit,Transmembrane AMPAR regulatory protein gamma-8,TARP gamma-8
4	G, J, M, O (A, C, D, B)	6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide	non-polymer		336.3	4	Chemie (E2Q)
5	H, I, K, L, N... (A, C, D, B)	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		790.1	6	Chemie (PC1)

Sequence modifications

A, C: -25 - 889 (UniProt: P19490)

PDB	External Database	Details
Asp -6	-	insertion
Tyr -5	-	insertion
Lys -4	-	insertion
Asp -3	-	insertion
Asp -2	-	insertion
Asp -1	-	insertion
Asp 0	-	insertion
Lys 1	-	insertion

D, B: -20 - 839 (UniProt: P19491)

PDB	External Database	Details
Arg 586	Gln 607	conflict

I, J: 2 - 417 (UniProt: Q8VHW5)

PDB	External Database	Details
Gly 1	-	expression tag
Leu 418	-	expression tag
Glu 419	-	expression tag
Val 420	-	expression tag
Leu 421	-	expression tag
Phe 422	-	expression tag
Gln 423	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	484970.0
Non-Polymers*	Number of molecules	10
	Total formula weight	6086.0
All*	Total formula weight	491056.0

*Water molecules are not included.