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7OCD

Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, C)
Isoform Flip of Glutamate receptor 1polymer915102661.92UniProt (P19490)
Pfam (PF01094)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Norway rat)GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1,GluA1
2C, F
(D, B)
Glutamate receptor 2polymer86096247.12UniProt (P19491)
Pfam (PF01094)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Norway rat)
3D, E
(I, J)
Voltage-dependent calcium channel gamma-8 subunitpolymer42343576.02UniProt (Q8VHW5)
Pfam (PF00822)
Rattus norvegicus (Norway rat)Neuronal voltage-gated calcium channel gamma-8 subunit,Transmembrane AMPAR regulatory protein gamma-8,TARP gamma-8
4G, J, M, O
(A, C, D, B)
6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamidenon-polymer336.34Chemie (E2Q)
5H, I, K, L, N...
(A, C, D, B)
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer790.16Chemie (PC1)
Sequence modifications
A, C: -25 - 889 (UniProt: P19490)
PDBExternal DatabaseDetails
Asp -6-insertion
Tyr -5-insertion
Lys -4-insertion
Asp -3-insertion
Asp -2-insertion
Asp -1-insertion
Asp 0-insertion
Lys 1-insertion
D, B: -20 - 839 (UniProt: P19491)
PDBExternal DatabaseDetails
Arg 586Gln 607conflict
I, J: 2 - 417 (UniProt: Q8VHW5)
PDBExternal DatabaseDetails
Gly 1-expression tag
Leu 418-expression tag
Glu 419-expression tag
Val 420-expression tag
Leu 421-expression tag
Phe 422-expression tag
Gln 423-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight484970.0
Non-Polymers*Number of molecules10
Total formula weight6086.0
All*Total formula weight491056.0
*Water molecules are not included.

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PDB entries from 2024-10-30

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