7OCD
Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, C) | Isoform Flip of Glutamate receptor 1 | polymer | 915 | 102661.9 | 2 | UniProt (P19490) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1,GluA1 |
2 | C, F (D, B) | Glutamate receptor 2 | polymer | 860 | 96247.1 | 2 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | |
3 | D, E (I, J) | Voltage-dependent calcium channel gamma-8 subunit | polymer | 423 | 43576.0 | 2 | UniProt (Q8VHW5) Pfam (PF00822) | Rattus norvegicus (Norway rat) | Neuronal voltage-gated calcium channel gamma-8 subunit,Transmembrane AMPAR regulatory protein gamma-8,TARP gamma-8 |
4 | G, J, M, O (A, C, D, B) | 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide | non-polymer | 336.3 | 4 | Chemie (E2Q) | |||
5 | H, I, K, L, N... (A, C, D, B) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 6 | Chemie (PC1) |
Sequence modifications
A, C: -25 - 889 (UniProt: P19490)
D, B: -20 - 839 (UniProt: P19491)
I, J: 2 - 417 (UniProt: Q8VHW5)
PDB | External Database | Details |
---|---|---|
Asp -6 | - | insertion |
Tyr -5 | - | insertion |
Lys -4 | - | insertion |
Asp -3 | - | insertion |
Asp -2 | - | insertion |
Asp -1 | - | insertion |
Asp 0 | - | insertion |
Lys 1 | - | insertion |
PDB | External Database | Details |
---|---|---|
Arg 586 | Gln 607 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Leu 418 | - | expression tag |
Glu 419 | - | expression tag |
Val 420 | - | expression tag |
Leu 421 | - | expression tag |
Phe 422 | - | expression tag |
Gln 423 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 484970.0 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 6086.0 | |
All* | Total formula weight | 491056.0 |