7OAM
Kinase domain of MERTK in complex with compound 8
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Tyrosine-protein kinase Mer | polymer | 296 | 34074.5 | 2 | UniProt (Q12866) Pfam (PF07714) In PDB | Homo sapiens (Human) | Proto-oncogene c-Mer,Receptor tyrosine kinase MerTK |
2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
3 | B | 2-[[2,5-bis(fluoranyl)phenyl]methylamino]-4-(cyclopentylamino)-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide | non-polymer | 472.5 | 1 | Chemie (V6H) | |||
4 | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A, B: 571 - 863 (UniProt: Q12866)
PDB | External Database | Details |
---|---|---|
Ser 569 | - | expression tag |
Met 570 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 68149.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 658.7 | |
All* | Total formula weight | 68807.7 |