7OAK
Crystal structure of pseudokinase CASK in complex with compound 26
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Peripheral plasma membrane protein CASK | polymer | 353 | 39505.4 | 4 | UniProt (O14936) Pfam (PF00069) | Homo sapiens (Human) | hCASK,Calcium/calmodulin-dependent serine protein kinase,Protein lin-2 homolog |
| 2 | E, K, R, W (A, B, C, D) | 2-[[2,5-bis(bromanyl)-4-methyl-phenyl]methylamino]-4-(cyclopentylamino)-N-[3-(2-oxidanylidene-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide | non-polymer | 610.3 | 4 | Chemie (V6B) | |||
| 3 | AA, BA, F, G, H... (D, A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 20 | Chemie (EDO) | |||
| 4 | CA, DA, EA, FA (A, B, C, D) | water | water | 18.0 | 394 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 337 (UniProt: O14936)
| PDB | External Database | Details |
|---|---|---|
| Ser -15 | - | expression tag |
| Met -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Pro -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ile -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ile -2 | - | expression tag |
| Arg -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 158021.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 3682.7 | |
| All* | Total formula weight | 161704.5 |
