7OAJ
Crystal structure of pseudokinase CASK in complex with compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Peripheral plasma membrane protein CASK | polymer | 353 | 39505.4 | 4 | UniProt (O14936) Pfam (PF00069) | Homo sapiens (Human) | hCASK,Calcium/calmodulin-dependent serine protein kinase,Protein lin-2 homolog |
| 2 | AA, E, L, U (D, A, B, C) | 4-(cyclopentylamino)-2-[(3,4-dichlorophenyl)methylamino]-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide | non-polymer | 505.4 | 4 | Chemie (V6E) | |||
| 3 | BA, CA, DA, F, G... (D, A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 22 | Chemie (EDO) | |||
| 4 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 549 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 337 (UniProt: O14936)
| PDB | External Database | Details |
|---|---|---|
| Ser -15 | - | expression tag |
| Met -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Pro -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ile -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ile -2 | - | expression tag |
| Arg -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 158021.8 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 3387.3 | |
| All* | Total formula weight | 161409.0 |
