Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
C | 0004672 | molecular_function | protein kinase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0006468 | biological_process | protein phosphorylation |
D | 0004672 | molecular_function | protein kinase activity |
D | 0005524 | molecular_function | ATP binding |
D | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | binding site for residue V6E A 401 |
Chain | Residue |
A | ILE18 |
A | CYS146 |
A | LEU148 |
A | GLY161 |
A | GLY162 |
A | HOH517 |
A | GLY19 |
A | ALA39 |
A | GLU92 |
A | PHE93 |
A | MET94 |
A | ASP95 |
A | GLY96 |
A | LYS105 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue EDO A 402 |
Chain | Residue |
A | ARG28 |
A | ILE30 |
B | HIS287 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue EDO A 403 |
Chain | Residue |
A | SER24 |
A | LYS41 |
A | PHE48 |
A | LEU59 |
A | GLU62 |
A | HOH605 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue EDO A 404 |
Chain | Residue |
A | CYS66 |
A | ILE74 |
A | VAL75 |
A | LEU77 |
A | PHE163 |
A | HOH563 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue EDO A 405 |
Chain | Residue |
A | ARG130 |
A | ASP134 |
A | TYR268 |
A | HOH511 |
A | HOH575 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue EDO A 406 |
Chain | Residue |
A | ASN136 |
A | GLU171 |
A | GLY173 |
B | GLU247 |
B | ASP251 |
B | HOH558 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue EDO A 407 |
Chain | Residue |
A | LEU217 |
A | TYR220 |
A | HOH576 |
site_id | AC8 |
Number of Residues | 15 |
Details | binding site for residue V6E B 401 |
Chain | Residue |
B | ILE18 |
B | GLY19 |
B | ALA39 |
B | PHE91 |
B | GLU92 |
B | PHE93 |
B | MET94 |
B | ASP95 |
B | GLY96 |
B | LYS105 |
B | CYS146 |
B | LEU148 |
B | GLY161 |
B | GLY162 |
B | HOH590 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue EDO B 402 |
Chain | Residue |
A | GLU247 |
A | ASP251 |
B | ASN136 |
B | GLU171 |
B | LYS198 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue EDO B 403 |
Chain | Residue |
A | VAL112 |
A | HIS287 |
B | ARG28 |
B | ILE30 |
site_id | AD2 |
Number of Residues | 5 |
Details | binding site for residue EDO B 404 |
Chain | Residue |
B | SER24 |
B | LYS41 |
B | VAL43 |
B | GLU62 |
B | HOH563 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue EDO B 405 |
Chain | Residue |
B | LYS70 |
B | HIS71 |
B | HOH507 |
B | HOH551 |
site_id | AD4 |
Number of Residues | 3 |
Details | binding site for residue EDO B 406 |
Chain | Residue |
B | PHE101 |
B | HIS145 |
B | ARG302 |
site_id | AD5 |
Number of Residues | 2 |
Details | binding site for residue EDO B 407 |
Chain | Residue |
B | ALA97 |
B | PHE101 |
site_id | AD6 |
Number of Residues | 4 |
Details | binding site for residue EDO B 408 |
Chain | Residue |
B | LYS70 |
B | CYS216 |
B | LEU217 |
B | TYR220 |
site_id | AD7 |
Number of Residues | 4 |
Details | binding site for residue EDO B 409 |
Chain | Residue |
A | GLU269 |
B | TYR235 |
B | ARG254 |
B | HOH514 |
site_id | AD8 |
Number of Residues | 14 |
Details | binding site for residue V6E C 401 |
Chain | Residue |
C | LEU148 |
C | GLY161 |
C | GLY162 |
C | HOH547 |
C | ILE18 |
C | GLY19 |
C | ALA39 |
C | GLU92 |
C | MET94 |
C | ASP95 |
C | GLY96 |
C | ALA97 |
C | LYS105 |
C | CYS146 |
site_id | AD9 |
Number of Residues | 4 |
Details | binding site for residue EDO C 402 |
Chain | Residue |
C | ARG28 |
C | ILE30 |
D | ILE286 |
D | HIS287 |
site_id | AE1 |
Number of Residues | 3 |
Details | binding site for residue EDO C 403 |
Chain | Residue |
C | SER24 |
C | LYS41 |
C | GLU62 |
site_id | AE2 |
Number of Residues | 3 |
Details | binding site for residue EDO C 404 |
Chain | Residue |
C | HIS120 |
C | SER155 |
C | HOH560 |
site_id | AE3 |
Number of Residues | 4 |
Details | binding site for residue EDO C 405 |
Chain | Residue |
C | CYS216 |
C | LEU217 |
C | TYR220 |
C | HOH561 |
site_id | AE4 |
Number of Residues | 3 |
Details | binding site for residue EDO C 406 |
Chain | Residue |
C | TYR235 |
C | ARG254 |
D | GLU269 |
site_id | AE5 |
Number of Residues | 13 |
Details | binding site for residue V6E D 401 |
Chain | Residue |
D | ILE18 |
D | ALA39 |
D | PHE91 |
D | GLU92 |
D | PHE93 |
D | MET94 |
D | ASP95 |
D | GLY96 |
D | LYS105 |
D | CYS146 |
D | LEU148 |
D | GLY161 |
D | GLY162 |
site_id | AE6 |
Number of Residues | 4 |
Details | binding site for residue EDO D 402 |
Chain | Residue |
C | VAL112 |
C | HIS287 |
D | ARG28 |
D | ILE30 |
site_id | AE7 |
Number of Residues | 6 |
Details | binding site for residue EDO D 403 |
Chain | Residue |
D | SER24 |
D | LYS41 |
D | VAL43 |
D | PHE48 |
D | GLU62 |
D | HOH591 |
site_id | AE8 |
Number of Residues | 7 |
Details | binding site for residue EDO D 404 |
Chain | Residue |
C | GLU247 |
C | HOH545 |
D | ASN136 |
D | GLY170 |
D | GLU171 |
D | GLY173 |
D | LYS198 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: ACT_SITE => ECO:0000250 |
Chain | Residue | Details |
A | ASP141 | |
B | ASP141 | |
C | ASP141 | |
D | ASP141 | |
Chain | Residue | Details |
A | ILE18 | |
B | ILE18 | |
C | ILE18 | |
D | ILE18 | |
Chain | Residue | Details |
A | LYS41 | |
B | LYS41 | |
C | LYS41 | |
D | LYS41 | |
Chain | Residue | Details |
A | SER51 | |
B | SER51 | |
C | SER51 | |
D | SER51 | |
Chain | Residue | Details |
A | SER151 | |
A | SER155 | |
B | SER151 | |
B | SER155 | |
C | SER151 | |
C | SER155 | |
D | SER151 | |
D | SER155 | |
Chain | Residue | Details |
A | THR182 | |
B | THR182 | |
C | THR182 | |
D | THR182 | |
Chain | Residue | Details |
A | SER313 | |
B | SER313 | |
C | SER313 | |
D | SER313 | |