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7O6X

Tankyrase 2 in complex with an inhibitor (OM-153)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1BBB, AAAPoly [ADP-ribose] polymerase tankyrase-2polymer17119482.12UniProt (Q9H2K2)
Pfam (PF00644)
In PDB
Homo sapiens (human)ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
2A, BPoly [ADP-ribose] polymerase tankyrase-2polymer485364.02UniProt (Q9H2K2)
In PDB
Homo sapiens (human)ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
3BBB, AAAN-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]quinoxaline-5-carboxamidenon-polymer509.52Chemie (V4Q)
4BBB, AAAZINC IONnon-polymer65.42Chemie (ZN)
5waterwater18.0124Chemie (HOH)
Sequence modifications
BBB, AAA: 946 - 1114 (UniProt: Q9H2K2)
PDBExternal DatabaseDetails
Ser 944-expression tag
Met 945-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight49692.2
Non-Polymers*Number of molecules4
Total formula weight1149.9
All*Total formula weight50842.1
*Water molecules are not included.

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PDB entries from 2024-04-24

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