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7O5Z

Human phosphomannomutase 2 (PMM2) with mutation T237M in apo state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Phosphomannomutase 2polymer24828304.42UniProt (O15305)
Pfam (PF03332)
Homo sapiens (Human)PMM 2
2C, D, E, F, J...
(A, B)
GLYCEROLnon-polymer92.18Chemie (GOL)
3G, H, N, O
(A, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4I, P
(A, B)
SODIUM IONnon-polymer23.02Chemie (NA)
5Q
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6R, S
(A, B)
waterwater18.0243Chemie (HOH)
Sequence modifications
A, B: 1 - 246 (UniProt: O15305)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Met 237Thr 237engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight56608.9
Non-Polymers*Number of molecules15
Total formula weight915.4
All*Total formula weight57524.3
*Water molecules are not included.

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PDB entries from 2026-02-04

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