7O58
Human phosphomannomutase 2 (PMM2) with mutation T237M in complex with the activator glucose 1,6-bisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphomannomutase 2 | polymer | 248 | 28304.4 | 2 | UniProt (O15305) Pfam (PF03332) | Homo sapiens (Human) | PMM 2 |
| 2 | C, D, E, F, H... (A, B) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 3 | G (A) | 1,6-di-O-phosphono-alpha-D-glucopyranose | non-polymer | 339.1 | 1 | Chemie (G16) | |||
| 4 | I, J, R, S (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | K (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | L, M, T (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 7 | U, V (A, B) | water | water | 18.0 | 297 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 246 (UniProt: O15305)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Met 237 | Thr 237 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56608.9 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1369.6 | |
| All* | Total formula weight | 57978.5 |
