7O58
Human phosphomannomutase 2 (PMM2) with mutation T237M in complex with the activator glucose 1,6-bisphosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004615 | molecular_function | phosphomannomutase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006013 | biological_process | mannose metabolic process |
| A | 0006487 | biological_process | protein N-linked glycosylation |
| A | 0009101 | biological_process | glycoprotein biosynthetic process |
| A | 0009298 | biological_process | GDP-mannose biosynthetic process |
| A | 0043025 | cellular_component | neuronal cell body |
| A | 0061728 | biological_process | GDP-mannose biosynthetic process from mannose |
| A | 0061729 | biological_process | GDP-D-mannose biosynthetic process from fructose-6-phosphate |
| B | 0004615 | molecular_function | phosphomannomutase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006013 | biological_process | mannose metabolic process |
| B | 0006487 | biological_process | protein N-linked glycosylation |
| B | 0009101 | biological_process | glycoprotein biosynthetic process |
| B | 0009298 | biological_process | GDP-mannose biosynthetic process |
| B | 0043025 | cellular_component | neuronal cell body |
| B | 0061728 | biological_process | GDP-mannose biosynthetic process from mannose |
| B | 0061729 | biological_process | GDP-D-mannose biosynthetic process from fructose-6-phosphate |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"Q92871","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"Q92871","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q92871","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P31353","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9Z2M7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
