7O4W
Crystal structure of diphtheria toxin mutant CRM197 with a disulphide bond replaced by a Cys-Acetone-Cys bridge
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Diphtheria toxin | polymer | 535 | 58483.4 | 1 | UniProt (Q5PY51) Pfam (PF02763) Pfam (PF02764) Pfam (PF01324) UniProt (by SIFTS) (Q6NK15) | Corynebacterium diphtheriae | |
| 2 | B (A) | 1-hydroxypropan-2-one | non-polymer | 74.1 | 1 | Chemie (4Y8) | |||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | F, G (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 5 | H (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | I (A) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 1 - 535 (UniProt: Q5PY51)
| PDB | External Database | Details |
|---|---|---|
| Glu 52 | Gly 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58483.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 619.7 | |
| All* | Total formula weight | 59103.1 |
