7O3L

Crystal Structure of AcrB Double Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Efflux pump membrane transporter	polymer	1069	115684.3	6	UniProt (E2QH56) Pfam (PF00873) UniProt (by SIFTS) (P31224) In PDB	Escherichia coli
2	A, B, C, D, E...	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	6	Chemie (LMT)

Sequence modifications

A, B, C, D, E, F: 1 - 1049 (UniProt: E2QH56)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ala 615	Phe 615	engineered mutation
Ala 617	Phe 617	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	694105.8
Non-Polymers*	Number of molecules	6
	Total formula weight	3063.7
All*	Total formula weight	697169.5

*Water molecules are not included.